Protein Alignment alpha-Est1 and cest-10

DIOPT Version :9

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_501133.3
• Gene: cest-10 / 177493
• WormBaseID: WBGene00016595
• Length: 579
• Species: Caenorhabditis elegans
• Alignment Length: 498
• Identity: 117/498 - (23%)
• Similarity: 205/498 - (41%)
• Gaps: 121/498 - (24%)

  Fly    56 YFAFEGIPFAQPPVGELRFRAPQPPHPWLGVRDC-TYPRA--------KPMQKHFVLSIVEGSED 111
            :..|:.||||:||:|:|||:.|||...|.|||:. .|..|        |.:||..       .||
 Worm    39 FHLFKKIPFAKPPLGKLRFQKPQPAETWNGVRNAKDYGPACMSNSSTTKTVQKWV-------DED 96

  Fly   112 CLYLNVY-SKRLRSDKPLPVIVWIYGGGFQFGEA--GRDFYSPDYFMQQDVVVVTFNYRVGALGF 173
            ||:||:: |:.....|...|:::::||...:..|  ..|.:....:..|::|.|....|:|....
 Worm    97 CLHLNIFTSETCLKSKNCAVVIYLHGGNLHYDSAVMFNDTFLLHTYASQEIVFVIPAVRLGIFSH 161

  Fly   174 LSLADRDLDVPGNAGLKDQVMALRWISQNIAQFNGDPQNITVMGESAG--AASVHALMTTEQT-R 235
            ..:.|:.: .|.|..|.|.:.|:.:...:|..|.|:.:..|::|.|.|  .||:.:..|...| .
 Worm   162 FVVEDQSI-APNNLALFDMLQAMEFAKSDIHNFGGNNKRTTLLGHSYGGTVASMLSFSTKVNTDL 225

  Fly   236 GLFHKAI-MQSGSMF--CEWANEPSGRWAYRLACQLGYSG--SENEKEVFR--YLQKAPASEMAA 293
            .||.:.| |.|.:.|  .|...|.:.|:|....|....|.  .:|:|||:.  .|:|..|||:
 Worm   226 SLFQQYISMSSPTNFDTLELQVERTYRFAEHANCLPKNSKFMRKNQKEVYMRDCLKKKSASEL-- 288

  Fly   294 QGITLVSQEERRQYVLFPFT----PVVEPYITRDCVLPRCHREMLPEAWGNDLPLILGGNSFEGL 354
              :.:....|...|.::..:    |:.:..:.||.:               |.|..:  .|..|.
 Worm   289 --LRIQRSLEEAGYPVYGGSVMRGPIFQEVLERDFM---------------DSPNNI--TSLTGC 334

  Fly   355 FSYQSTLHDEEHMLSAFEVLIPREIREKSTQSHLKDLLRQFKVDNFD--------DATRGRMEFN 411
            ..|:|.::|                       |.:::.:....:|::        |:..|::||:
 Worm   335 TKYESLVYD-----------------------HYRNMGKALGFENYEEVNEKYRSDSKEGKIEFD 376

  Fly   412 ECLHILSVKHFWHGIHRTVLARLS-----HAPATPTYLYRFDVDSPHFNHFRQVMCGKHVRGVSH 471
                  :||:....:...:..|::     :.||     |.::...|           ||   .:|
 Worm   377 ------NVKNATQIMLIQIRTRVNKILKKNIPA-----YHYEYAYP-----------KH---ANH 416

  Fly   472 ADDLSYLF-YHILANKVDKSSMEYQTIQRLVGMWVAFARNDNP 513
            .|||.::. .|....  |::.::.....|  .|::.|.:..||
 Worm   417 TDDLFFIMGVHPFIQ--DENEIKLGNFYR--SMFLNFIKTGNP 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	117/498 (23%)
		Aes	<117..>233	CDD:223730	28/120 (23%)
cest-10	NP_501133.3	Abhydrolase	23..503	CDD:389770	117/498 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156924
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740