DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alpha-Est1 and LOC107987423

DIOPT Version :9

Sequence 1:	NP_524269.3	Gene:	alpha-Est1 / 40909	FlyBaseID:	FBgn0015568	Length:	565	Species:	Drosophila melanogaster
Sequence 2:	XP_016885725.1	Gene:	LOC107987423 / 107987423	-ID:	-	Length:	286	Species:	Homo sapiens

Alignment Length:	251	Identity:	61/251 - (24%)
Similarity:	101/251 - (40%)	Gaps:	38/251 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   325 VLPRCHREMLPEAWGNDLPLILGGNSFE-------GLFSY---QSTLHDEEHMLSAFE----VLI 375
            :|.:...|:..|...:.:|.::|.|..|       .|.||   :..|..:..|...::    |.|
Human    46 LLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCI 110

  Fly   376 PREIREKSTQSHLKDLLRQFKVDNFDDATRGRMEFNECLHILSVKHFWHGIHRTVLARLSHAPAT 440
            .:|:..::|:.:|         ...||..:.:..|   |.:::...|  |:...::||.......
Human   111 AKELIPEATEKYL---------GGTDDTVKKKDLF---LDLIADVMF--GVPSVIVARNHRDAGA 161

  Fly   441 PTYLYRFDVDSPHFNHFRQVMCGKHVRGVSHADDLSYLFYHILANKVDKSSMEYQTIQRLVGMWV 505
            |||:|.|.. .|.|:   ..|..|.|.| .|.|:|..:|..... |...|..|.:..:.::..|.
Human   162 PTYMYEFQY-RPSFS---SDMKPKTVIG-DHGDELFSVFGAPFL-KEGASEEEIRLSKMVMKFWA 220

  Fly   506 AFARNDNPNCPQIGPTTWEALDEKGPQMCLNIGKQLEFIVLPESKQNRIWDRLYDK 561
            .||||.|||..  |...|...::|  :..|.||...:.....:.|:...|..|:.|
Human   221 NFARNGNPNGE--GLPHWPEYNQK--EGYLQIGANTQAAQKLKDKEVAFWTNLFAK 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	57/229 (25%)
alpha-Est1	NP_524269.3	Aes	<117..>233	CDD:223730
LOC107987423	XP_016885725.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010