Protein Alignment alpha-Est1 and Ces2a

DIOPT Version :9

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_598721.1
• Gene: Ces2a / 102022
• MGIID: 2142491
• Length: 558
• Species: Mus musculus
• Alignment Length: 574
• Identity: 175/574 - (30%)
• Similarity: 255/574 - (44%)
• Gaps: 123/574 - (21%)

  Fly    37 TRDGQVRG---HRRRTLYDEEMYFAFEGIPFAQPPVGELRFRAPQPPHPWLGVRD-------CTY 91
            |..|||||   |.:.|   :....||.|||||:||||.|||..|:.|.||.||||       |..
Mouse    36 THRGQVRGSFVHVKDT---KSGVHAFLGIPFAKPPVGLLRFAPPEDPEPWSGVRDGTSQPAMCLQ 97

  Fly    92 P------RAKPMQKHFVLSIVEGSEDCLYLNVYS-KRLRSDKPLPVIVWIYGGGFQFGEAGRDFY 149
            |      .||.|  :.:|..:..||||||||:|: ...:....|||:|||:|||...|.|..:..
Mouse    98 PDIMNLEDAKEM--NLILPPISMSEDCLYLNIYTPTHAQEGSNLPVMVWIHGGGLVVGSASMNDV 160

  Fly   150 SPDYFMQQDVVVVTFNYRVGALGFLSLADRDLDVPGNAGLKDQVMALRWISQNIAQFNGDPQNIT 214
            | .....:::|:|...||:|.|||.|..|:  ...||.|..|||.||||:.:|||.|.|:...:|
Mouse   161 S-KLAATEEIVIVAIQYRLGVLGFFSTGDQ--HARGNWGYLDQVAALRWVQKNIAYFGGNRDRVT 222

  Fly   215 VMGESAGAASVHALMTTEQTRGLFHKAIMQSGSMFCEWANEPSGRWAYRLACQLGYSGSE-NEKE 278
            :.|.|||..||.:.:.:..::||||.||||||..........:....|:....|  ||.| .:.|
Mouse   223 IFGVSAGGTSVSSHILSPMSKGLFHGAIMQSGVALLPDLISDTSEVVYKTVANL--SGCEATDSE 285

  Fly   279 VFRYLQKAPASEMAAQGITLVSQEERRQYVLFPFTPVVEPYITRDCVLPRCHREMLPEAWGNDLP 343
            ...:..:|.:.    |.|..::|       :|...|.|    .....||:..:|:|.....:.:|
Mouse   286 ALIHCLRAKSK----QEILAINQ-------VFKMIPAV----VDGEFLPKHPQELLTSMDFHPVP 335

  Fly   344 LILGGNS---------FEGLFSYQSTLHDEEHML--------------SAFEVLIPREIREKSTQ 385
            .|:|.|:         |.||          :|::              :|..:::|.|.
Mouse   336 SIIGVNTDECGWGVPMFMGL----------DHIIKNITRETLPAVLKNTAARMMLPPEC------ 384

  Fly   386 SHLKDLLRQFKVDNFDDATRGRMEFNECL-------HILSVKHFWHGIHRTVLARLSHAPATPTY 443
            |||  |:.::..|..|..|. :.:|.|.|       ..|.|.||          :.|.|   |.|
Mouse   385 SHL--LVEEYMGDTEDPETL-QAQFREMLGDFMFVIPALQVAHF----------QRSQA---PVY 433

  Fly   444 LYRFDVDSPHFNHFRQVMCGKHVRGVSHADDLSYLFYHILAN-KVDKSSMEYQTIQRLVGMWVAF 507
            .|.|...|....|.|.    .||: ..|.||::::|...|.: .:|.:..|....:.::..|..|
Mouse   434 FYEFQHLSSFIKHVRP----SHVK-ADHGDDVAFVFGSYLWDMNLDLTEEEELLKRMMMKYWANF 493

  Fly   508 ARNDNPNCPQIGPTTWEALDEKGPQMCLN----IGKQLEFIVLPESKQNRIWDR 557
            |||.|||..  |..:|..||.....:.|:    :|:.|      ::::.:.|.:
Mouse   494 ARNGNPNSE--GLPSWPVLDHDEQYLQLDTQPAVGRAL------KARRLQFWTK 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	173/556 (31%)
		Aes	<117..>233	CDD:223730	45/116 (39%)
Ces2a	NP_598721.1	COesterase	30..537	CDD:278561	174/570 (31%)
		Aes	<127..>230	CDD:223730	42/105 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832750
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.640