Protein Alignment alpha-Est1 and Ces2

DIOPT Version :9

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_001258232.1
• Gene: Ces2 / 100910144
• RGDID: 6504334
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 541
• Identity: 174/541 - (32%)
• Similarity: 256/541 - (47%)
• Gaps: 86/541 - (15%)

  Fly    23 VQYRLGTKQTKVVCTRDGQVRGHRRRTLYDEEMYFAFEGIPFAQPPVGELRFRAPQPPHPWLGVR 87
            ||.:...:.:.:..|..|||:|........:.....|.|||||:||||.|||..|:||.||.|||
  Rat    24 VQGQDSPESSPIRTTHTGQVQGKLDHVKDTKAGVHTFLGIPFAKPPVGPLRFAPPEPPEPWSGVR 88

  Fly    88 DCTYPRAKPMQK------------HFVLSIVEGSEDCLYLNVYS-KRLRSDKPLPVIVWIYGGGF 139
            |.|...|..:|.            ..:||.:..||||||||||: ...|....|||:|||:||..
  Rat    89 DATSQPAMCLQNLDILDEVGLLDMKMILSSISMSEDCLYLNVYAPAHAREGSNLPVMVWIHGGAL 153

  Fly   140 QFGEAGRDFYSPDYF-MQQDVVVVTFNYRVGALGFLSLADRDLDVPGNAGLKDQVMALRWISQNI 203
            ..|.|  ..|..... :.:|:||||..||:|.|||.|..|.  ...||.|..|||.||||:.|||
  Rat   154 VVGMA--SMYDGSLLTVNEDLVVVTIQYRLGVLGFFSTGDE--HARGNWGYLDQVAALRWVQQNI 214

  Fly   204 AQFNGDPQNITVMGESAGAASVHALMTTEQTRGLFHKAIMQSG-SMFCEWANEPSGRWAYRLACQ 267
            |.|.|:|..:|:.|||||..||.:.:.:..::||||.|||:|| ::..:..:|.|...:..:|..
  Rat   215 AHFGGNPNRVTIFGESAGGTSVSSHVISPMSQGLFHGAIMESGVALLPDLISETSETVSTTVAKL 279

  Fly   268 LGYSGSENEKEVFRYLQKAPASEMAAQGITLVSQEERRQYVLFPFTPVVEPYITRDCVLPRCHRE 332
            .|....::|..| |.|:....:|     |.::::       :|...|.|    .....|||..:|
  Rat   280 SGCEAMDSEALV-RCLRAKSGAE-----ILVINK-------VFKMIPAV----VDGEFLPRHPKE 327

  Fly   333 MLPEAWGNDLPLILGGNSFEGLFSYQSTLHDEEHMLSAFEVLIPREIREKSTQSHLK-------- 389
            :|.....:.:|.|:|.|:.|    |..|:   ..::...:::  :|:..::.|:.||
  Rat   328 LLASEDFHPVPSIIGVNTDE----YCCTI---PMVMGTAQII--KELSRENLQAVLKDTAAQMML 383

  Fly   390 -----DLLRQFKVDNFDDATRGRMEFNE-------CLHILSVKHFWHGIHRTVLARLSHAPATPT 442
                 |||.:..:.|.||:...::::.|       .:..|.|.||          :.|||   |.
  Rat   384 PPECGDLLMEEYMGNTDDSQTLQIQYTEMMGDFLFVIPALQVAHF----------QRSHA---PV 435

  Fly   443 YLYRFDVDSPHFNHFRQVMCGKHVRGVSHADDLSYLFYHILAN-KVDKSSMEYQTIQRLVGMWVA 506
            |.|.|.....:|.:.|.    .||: ..|||::.::|....:. |:|.:..|....:|::..|..
  Rat   436 YFYEFQHAPSYFKNVRP----PHVK-ADHADEVPFVFGSFFSGMKLDFTEEERLLSRRMMKYWAN 495

  Fly   507 FARNDNPNCPQIGPTTWEALD 527
            |||..|||..  |...|.|||
  Rat   496 FARQGNPNSE--GLPYWPALD 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	172/536 (32%)
		Aes	<117..>233	CDD:223730	52/117 (44%)
Ces2	NP_001258232.1	COesterase	31..540	CDD:278561	172/534 (32%)
		Aes	<130..>233	CDD:223730	49/106 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336354
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830