Protein Alignment alpha-Est1 and ache

DIOPT Version :9

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: XP_002940088.1
• Gene: ache / 100490673
• XenbaseID: XB-GENE-923160
• Length: 600
• Species: Xenopus tropicalis
• Alignment Length: 597
• Identity: 171/597 - (28%)
• Similarity: 249/597 - (41%)
• Gaps: 140/597 - (23%)

  Fly    34 VVCTRDGQVRGHRRRTLYDEEMYFAFEGIPFAQPPVGELRFRAPQPPHPWLGVRDCT-YPRA--- 94
            :|.||.|:|||.|:..|  .....||.|||||:|||.::|||..:|..||..|.|.| ||.|
 Frog    30 LVSTRSGKVRGLRQPVL--STHVSAFLGIPFAEPPVDKMRFRRSEPKKPWTDVWDATAYPNACYQ 92

  Fly    95 ------------------KPMQKHFVLSIVEGSEDCLYLNVYSKRLRSDKPLPVIVWIYGGGFQF 141
                              :||           ||||||||::....|... ..|:||||||||..
 Frog    93 YFDTLYPGFPGMEMWNPNRPM-----------SEDCLYLNIWVPHPRPSN-ATVMVWIYGGGFYS 145

  Fly   142 GEAGRDFYSPDYFMQ-QDVVVVTFNYRVGALGFLSLADRDLDVPGNAGLKDQVMALRWISQNIAQ 205
            |.:..|.|...|... ::|:||:.||||||.|||:|....:|.|||.||.||.:||:|:..|||.
 Frog   146 GSSSLDVYDGRYLCHAENVIVVSMNYRVGAFGFLTLTPGSVDAPGNVGLFDQRLALQWVQDNIAF 210

  Fly   206 FNGDPQNITVMGESAGAASVHALMTTEQTRGLFHKAIMQSGSMFCEWA----------NEPSGRW 260
            |.|||:.:|:.||||||.||...:.:..:..||.||.:||||....||          .|..|::
 Frog   211 FGGDPRTVTIFGESAGAVSVGMHVLSPGSHHLFSKAALQSGSPNTPWATITPQEARRRTELLGKF 275

  Fly   261 AYRLACQLGYSGSENEKEVFRYLQKAPASEMAAQGITLVSQEERRQYVLFPFTPVVEPYITRDCV 325
               |.|::|     |:.|:...|:.....|       |:..|         |:.:..|.:.|...
 Frog   276 ---LDCRMG-----NDTELLNCLRVKQPQE-------LIDHE---------FSVLPAPSVFRFAF 316

  Fly   326 LPRCHREMLPEA------WG--NDLPLILGGNSFEGLFSY------------QSTLHDEEHMLSA 370
            :|....:..||.      .|  ...|||:|.|..||  ||            ..:|...|..|..
 Frog   317 VPVPDADFFPEPPEILMNMGRFKPCPLIMGVNQNEG--SYFLLYGAPGFSKNNESLITREEFLGG 379

  Fly   371 FEVLIPREIREKSTQSHLKDLLRQFKVDNFDDATRGRMEFNECLHILSVKHFWHGIHRTVLARLS 435
            .::.:|     ::....|:.::.|:  .::.|...| ::..|.:..|...|       .|:..|:
 Frog   380 VKMSVP-----QANDIALEAVVMQY--TDWADEHAG-VKNREAMDQLVGDH-------NVICPLT 429

  Fly   436 H------APATPTYLYRFDVDSPHFNHFRQVMCGKHVRGVSHADDLSYLFYHILANKVDKSSMEY 494
            :      ......|.|.||       |....:......||.|..::.::|...|...::.:..|.
 Frog   430 YFAGKVAETGNRVYTYFFD-------HRASNLAWPQWMGVPHGYEIEFVFGLPLDANLNYTPQEE 487

  Fly   495 QTIQRLVGMWVAFARNDNPNCPQIGPTTWEALDEKGPQMCLNIGKQLEFIVLPESKQNRI----- 554
            ...:|::..|..|||..:||         |..|...|:..|....:..::.|.......:
 Frog   488 ALSRRMMRYWANFARTGDPN---------EGNDAHQPRWPLYTASEQRYMALNNKPYQELQGIRV 543

  Fly   555 -----WDRLYDK 561
                 |:|...|
 Frog   544 QTCMFWNRFLPK 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	167/565 (30%)
		Aes	<117..>233	CDD:223730	54/116 (47%)
ache	XP_002940088.1	COesterase	31..549	CDD:395084	168/588 (29%)
		AChE_tetra	564..597	CDD:400834

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910