Protein Alignment alpha-Est1 and nlgn3

DIOPT Version :9

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: XP_012823589.1
• Gene: nlgn3 / 100329188
• XenbaseID: XB-GENE-977261
• Length: 843
• Species: Xenopus tropicalis
• Alignment Length: 631
• Identity: 179/631 - (28%)
• Similarity: 269/631 - (42%)
• Gaps: 130/631 - (20%)

  Fly    32 TKVVCTRDGQVRGHR----RRTLYDEEMYFAFEGIPFAQPPVGELRFRAPQPPHPWLGVRDCTY- 91
            ::.|.|..|::||.|    ...|...:.|.   |:|:|.|||||.||..|:||..|.|:|:.|:
 Frog    35 SQTVNTHYGKLRGTRVPLPSEILGPVDQYL---GVPYAAPPVGEKRFLPPEPPPSWSGIRNATHF 96

  Fly    92 --------PRAKP---MQKHFV--LSIVEG-----SEDCLYLNVY-----SKRLRSD---KP--- 127
                    ..|.|   |...|.  |..|.|     ||||||||:|     .||:..:   ||
 Frog    97 SPVCPQNIQNAVPDIMMPVWFTSNLDTVTGYLQEQSEDCLYLNIYVPTEDVKRISKECVRKPNKK 161

  Fly   128 --------------------------------LPVIVWIYGGGFQFGEAGRDFYSPDYFMQQDVV 160
                                            .||:|:|:||.:..| :|............:||
 Frog   162 ICRKGGPSAKKQGEELSDNDEDEEGDIRDTGAKPVMVYIHGGSYMEG-SGNMIDGSVLASYGNVV 225

  Fly   161 VVTFNYRVGALGFLSLADRDLDVPGNAGLKDQVMALRWISQNIAQFNGDPQNITVMGESAGAASV 225
            |:|.|||||.|||||..|:  ...||.||.||:.||||:|:|:|.|.|||..|||.|...||:.|
 Frog   226 VITLNYRVGVLGFLSTGDQ--AAKGNYGLLDQIQALRWVSENVAFFGGDPHRITVFGSGIGASCV 288

  Fly   226 HALMTTEQTRGLFHKAIMQSGSMFCEWA-NEPSGRWAYRLACQLGYSGSENEKEVFRYLQKAPAS 289
            ..|..:..:.|||.:||:||||....|| |....::...||.::|.:..:....|....||: |.
 Frog   289 SLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTRLLAEKVGCNVLDTVDMVDCLRQKS-AK 352

  Fly   290 EMAAQGITLVSQEERRQYVLFPFTPVVEPYITRDCVLPRCHREMLPEAWGNDLPLILGGNSFEGL 354
            |:..|.|     :..|.:|.|      .|.|..| |:|.....::.:....:..::||.|..|||
 Frog   353 ELVEQDI-----QPARYHVAF------GPVIDGD-VIPDDPEILMEQGEFLNYDIMLGVNQGEGL 405

  Fly   355 FSYQSTLHDEEHML-SAFEVLIPREIREKSTQSHLKDLLRQ-FKVDNFDDATRGRMEF-NECLHI 416
            ...::.:..|:.:. |.|:..:...:.........||.||: .|....|.|.|...|. .:.|..
 Frog   406 KFVENVVDAEDGVSGSDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVA 470

  Fly   417 LSVKHFWHGIHRTVLARLSHAP-ATPTYLYRFDVDSPHFNHFRQVMCGKHVRGVSHADDLSYLFY 480
            |...|.|  :..:|:....||. .:|||.|.|      ::|.:.:|..... ..:|.|::.|:|.
 Frog   471 LFTDHQW--VEPSVVTADLHARYGSPTYFYAF------YHHCQSLMKPAWA-DAAHGDEVPYVFG 526

  Fly   481 HILANKVD-------KSSMEYQTIQRLVGMWVAFARNDNPNCP-------------QIGPTTWEA 525
            ..:....|       |:.:....:  ::..|..||:..:||.|             :.....|..
 Frog   527 VPMVGPTDLFPCNFSKNDVMLSAV--VMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSK 589

  Fly   526 LDEKGPQMCLNIGKQLEFIVLPESKQNRI--W----DRLYDKNDLF 565
            .:.: .|:.|:||  |:..|....:..::  |    ..||:.:|:|
 Frog   590 YNPR-DQLYLHIG--LKPRVRDHYRATKVAFWKHLVPHLYNLHDMF 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	172/599 (29%)
		Aes	<117..>233	CDD:223730	53/158 (34%)
nlgn3	XP_012823589.1	COesterase	31..618	CDD:278561	174/615 (28%)
		Aes	<195..>302	CDD:223730	50/109 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910