Protein Alignment alpha-Est1 and nlgn1

DIOPT Version :9

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: XP_017949302.2
• Gene: nlgn1 / 100329186
• XenbaseID: XB-GENE-6041753
• Length: 859
• Species: Xenopus tropicalis
• Alignment Length: 646
• Identity: 178/646 - (27%)
• Similarity: 275/646 - (42%)
• Gaps: 155/646 - (23%)

  Fly    34 VVCTRDGQVRGHRRRTLYDEEM--YFAFEGIPFAQPPVGELRFRAPQPPHPWLGVRDCTYPRAKP 96
            ||.|..|:|||.::. |.:|.:  ...|.|:|:|.||:||.||:.|:||..|..:::.|  :..|
 Frog    54 VVLTTYGKVRGFKKE-LNNEILGPVVQFLGVPYAAPPIGERRFQPPEPPTMWGDIKNST--QFAP 115

  Fly    97 MQKHFVLS----------------------IVEGSEDCLYLNVY------------------SKR 121
            :....::.                      :.:.||||||||:|                  .|.
 Frog   116 VCPQNIVGGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKI 180

  Fly   122 LRSDKPL--------------------------PVIVWIYGGGFQFGEAGRDFYSPDYFMQQDVV 160
            .|.:.||                          ||:|:|:||.:..| .|..|.........:|:
 Frog   181 CRKEGPLTKKQTDDLGDNEGAEDEDIRDSGGPKPVMVYIHGGSYMEG-TGNVFDGSVLASYGNVI 244

  Fly   161 VVTFNYRVGALGFLSLADRDLDVPGNAGLKDQVMALRWISQNIAQFNGDPQNITVMGESAGAASV 225
            |:|.|||:|.|||||..|:  ...||.||.|.:.||||.|:||..|.|||..|||.|..|||:.|
 Frog   245 VITVNYRLGVLGFLSTGDQ--ASKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGASCV 307

  Fly   226 HALMT---------TEQTRGLFHKAIMQSGSMFCEWA--NEPSGRWAYRLACQLGYSGSENEKEV 279
            :.|..         :..|:|||.:||.|||:....||  .:|: ::|..||.::|.:.|:: .|:
 Frog   308 NLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPA-KYARILATKVGCNMSDS-GEL 370

  Fly   280 FRYLQKAPASEMAAQGITLVSQEERRQYVLFPFTPVVEPYITRDCVLPRCHREMLPEAWGNDLPL 344
            ...|||.|..|:..|.|..|     |.::.|      .|.|..| |:|...:.::.:....:..:
 Frog   371 VECLQKKPYRELVDQDIQPV-----RYHIAF------GPVIDGD-VIPDDPQVLMEQGEFLNYDI 423

  Fly   345 ILGGNSFEGLFSYQSTLHDEEHMLSA-FEVLIPREIREKSTQSHLKDLLRQ-FKVDNFDDATRGR 407
            :||.|..|||...:||:..|:.:.|: |:..:...:......:..||:||: .|....|.|.|..
 Frog   424 MLGVNQGEGLKFVESTVDHEDGVSSSDFDFAVSNFVDNLYGYTEGKDILRETIKFMYTDWADRNN 488

  Fly   408 MEF-NECLHILSVKHFWHGIHRTVLARLSHAP-ATPTYLYRFDVDSPHFNHFR--QVMCGKHVRG 468
            .|. .:.|..|...|.|  :...|.....|:. .:|||.|.|      ::|.:  ||...   ..
 Frog   489 PETRRKTLLALFTDHQW--VAPAVATADLHSNFGSPTYFYAF------YHHCQTDQVPAW---AD 542

  Fly   469 VSHADDLSYLF-------YHILANKVDKSSMEYQTIQRLVGMWVAFARNDNPNCP---------- 516
            .||.|::.|:|       ..:......|:.:....:  ::..|..||:..:||.|
 Frog   543 ASHGDEIPYVFGIPMIGPTELFPCNFSKNDVMLSAV--VMTYWTNFAKTGDPNQPVPQDTKFIHT 605

  Fly   517 ---QIGPTTWEALDEKGPQMCLNIGKQLEFIVLPESKQN------RIW----DRLYDKNDL 564
               :.....|....:| .|:.|:||      :.|..|::      .:|    .||:..|||
 Frog   606 KPNRFEEVAWTRYSQK-DQLYLHIG------LKPRVKEHYRATKVNLWLELVPRLHVMNDL 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	170/611 (28%)
		Aes	<117..>233	CDD:223730	52/168 (31%)
nlgn1	XP_017949302.2	COesterase	52..646	CDD:395084	172/631 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910