Protein Alignment alpha-Est1 and nlgn4xb

DIOPT Version :9

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_001159809.1
• Gene: nlgn4xb / 100147967
• ZFINID: ZDB-GENE-100309-1
• Length: 795
• Species: Danio rerio
• Alignment Length: 610
• Identity: 174/610 - (28%)
• Similarity: 262/610 - (42%)
• Gaps: 120/610 - (19%)

  Fly    30 KQTK--VVCTRDGQVRGHR----RRTLYDEEMYFAFEGIPFAQPPVGELRFRAPQPPHPWLGVRD 88
            :||:  .|.|..|::||.|    ...|...|.   |.|:|:|..|.||.||:||:||..|.|:|:
Zfish    18 QQTQFITVTTNYGKLRGLRVALPSEILGPVEQ---FLGVPYAMAPTGERRFQAPEPPLSWPGIRN 79

  Fly    89 CTYPRAKPMQKHFV-----------------LSIV-----EGSEDCLYLNVY---SKRLRSDKPL 128
            .|  :..|:...|:                 |..|     :.||||||||:|   .:..:.|..|
Zfish    80 AT--QFAPVCPQFLEDRLLLTDMLPVWFTANLDTVATYVHDQSEDCLYLNIYVPTEEETQDDAGL 142

  Fly   129 -PVIVWIYGGGFQFGEAGRDFYSPDYFMQQDVVVVTFNYRVGALGFLSLADRDLDVPGNAGLKDQ 192
             ||:|:|:||.:..| .|............:|:|||.|||:|.|||||..|:  ...||.||.||
Zfish   143 KPVMVYIHGGSYVEG-TGNMIDGSVLASYGNVIVVTVNYRLGVLGFLSTGDQ--AAKGNYGLLDQ 204

  Fly   193 VMALRWISQNIAQFNGDPQNITVMGESAGAASVHALMTTEQTRGLFHKAIMQSGSMFCEWA-NEP 256
            :.||||:.:||..|:|||:.:|:.|..|||:.|..|..:..:..||.|||:.||:....|| |..
Zfish   205 IQALRWVKENIQSFSGDPERVTIFGSGAGASCVSLLTLSHYSEDLFQKAIIHSGTALSSWAVNYQ 269

  Fly   257 SGRWAYRLACQLGYSGSENEKEVFRYLQKAPASEMAAQGITLVSQEERRQYVLFPFTPVVEPYIT 321
            ..::...||.::| ...::..|:...||.....|:..|.||.....       ..|.||::
Zfish   270 PAKYTRLLAEKVG-CNEDDTLELIECLQSKNYKELIEQNITPAKYH-------IAFGPVID---- 322

  Fly   322 RDCVLPRCHREMLPEAWGNDLPLILGGNSFEGLFSYQSTLHDEEHMLS-AFEVLIPREIREKSTQ 385
             ..|:|...:.::.:....:..::||.|..||.......|..|:.:.| .||..|...:
Zfish   323 -GDVIPDDPQILMEQGEFLNYDIMLGVNQGEGYKFVDGILDSEDRVTSNDFEFAISEFV------ 380

  Fly   386 SHL------KDLLRQ---FKVDNFDDATRGRMEFNECLHILSVKHFWHGIHRTVLARLSHAP-AT 440
            .||      ||.||:   |...::.|.....|. .:.|..|...|.|  :...|.....||. .:
Zfish   381 DHLYGYPEGKDTLRETIKFMYTDWADRENPEMR-RKTLVALFTDHQW--VAPAVATADLHAQYGS 442

  Fly   441 PTYLYRFDVDSPHFNHFRQVMCGKHVRGV----SHADDLSYLFYHILANKVD-------KSSMEY 494
            |||.|.|      ::|     |...::..    ||.|:|.|:|...:....|       |:.:..
Zfish   443 PTYFYAF------YHH-----CQSDMKPAWADSSHGDELPYVFGIPMIGPTDLFNCNFSKNDIML 496

  Fly   495 QTIQRLVGMWVAFARNDNPNCP-------------QIGPTTWEALDEKGPQMCLNIGKQLEFIVL 546
            ..:  ::..|..||:..:||.|             :.....|...:.| .|:.|:||  |:..|.
Zfish   497 SAV--VMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPK-DQLYLHIG--LKPRVR 556

  Fly   547 PESKQNRI--W----DRLYDKNDLF 565
            ...:..:|  |    ..|::.|:||
Zfish   557 DHYRATKIAFWLELVPHLHNINELF 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	166/578 (29%)
		Aes	<117..>233	CDD:223730	48/119 (40%)
nlgn4xb	NP_001159809.1	COesterase	17..567	CDD:278561	169/594 (28%)
		Aes	70..>243	CDD:223730	66/177 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575660
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840