Protein Alignment alpha-Est1 and nlgn1

DIOPT Version :9

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: XP_017213657.1
• Gene: nlgn1 / 100002610
• ZFINID: ZDB-GENE-090918-1
• Length: 867
• Species: Danio rerio
• Alignment Length: 626
• Identity: 166/626 - (26%)
• Similarity: 259/626 - (41%)
• Gaps: 148/626 - (23%)

  Fly    34 VVCTRDGQVRGHRRRTLYDEEM--YFAFEGIPFAQPPVGELRFRAPQPPHPWLGVRDCTYPRAKP 96
            :|.|..|:|||.::. |.:|.:  ...|.|:|:|.||.||.||:.|:||..|..:|:.|  :..|
Zfish    55 IVTTTYGKVRGFKKE-LNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPISWSEIRNAT--QFAP 116

  Fly    97 MQKHFVLS----------------------IVEGSEDCLYLNVY--------------------- 118
            :....:|.                      :.:.|||||:||:|
Zfish   117 VCPQTLLEGRLPDVMLPVWFTNSIEVVSSYVQDQSEDCLFLNIYVPTEDVKRISKECARKPGKKI 181

  Fly   119 -------SKRLRSD----------------KPLPVIVWIYGGGFQFGEAGRDFYSPDYFMQQDVV 160
                   ||:...|                .|.||:|:::||.:..| .|..|.........:|:
Zfish   182 CRKGGPLSKKQNDDLADNDGAEDEDIRESGSPKPVMVFVHGGSYMEG-TGNMFDGSILASYGNVI 245

  Fly   161 VVTFNYRVGALGFLSLADRDLDVPGNAGLKDQVMALRWISQNIAQFNGDPQNITVMGESAGAASV 225
            |:|.|||:|.|||||..|:  ...||.||.|.:.||||.|:|||.|.|||..|||.|..|||:.|
Zfish   246 VITVNYRLGVLGFLSTGDQ--AAKGNYGLLDLIQALRWTSENIAFFGGDPLRITVFGSGAGASCV 308

  Fly   226 HALMT---------TEQTRGLFHKAIMQSGSMFCEWA--NEPSGRWAYRLACQLGYSGSENEKEV 279
            :.|..         :..|:|||.:||.|||:....||  .:|: ::|..||.::| ...::..|:
Zfish   309 NLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPA-KYARMLAKKVG-CNLKDTVEM 371

  Fly   280 FRYLQKAPASEMAAQGITLVSQEERRQYVLFPFTPVVEPYITRDCVLPRCHREMLPEAWGNDLPL 344
            ...|||....|:..|.|     :..|.::.|      .|.|..| |:|...:.::.:....:..:
Zfish   372 VECLQKKHYKELVEQDI-----QPARYHIAF------GPVIDGD-VIPDDPQILMEQGEFLNYDI 424

  Fly   345 ILGGNSFEGLFSYQSTLHDEEHMLSA--FEVLIPREIREKSTQSHLKDLLRQ-FKVDNFDDATRG 406
            :||.|..||| .:...:.|.|:.:.|  |:..:...:.:.......||:||: .|....|.|.|.
Zfish   425 MLGVNQGEGL-KFVELIVDNENGVQANDFDYAVSSFVDDLYGYPEGKDILRETIKFMYTDWADRH 488

  Fly   407 RMEF-NECLHILSVKHFWHGIHRTVLARLSHAPATPTYLYRFDVDSPHFNHFRQVMCGKHVRGVS 470
            ..|. .:.|..|...|.|.. .....|.|..:..:|||.|.|      ::|.:........ ..:
Zfish   489 NPETRRKTLLALFTDHQWVA-PAVATADLHSSFGSPTYFYAF------YHHCQTEQVPPWA-DAA 545

  Fly   471 HADDLSYLF-------YHILANKVDKSSMEYQTIQRLVGMWVAFARNDNPNCPQIGPTTWEALDE 528
            |.|::.|:|       ..:......|:.:....:  ::..|..||:..:||.|
Zfish   546 HGDEIPYVFGLPMIGPTELFPCNFSKNDVMLSAV--VMTYWTNFAKTGDPNQP------------ 596

  Fly   529 KGPQMCLNIGKQLEFIVLPESKQNRI----WDRLYDKNDLF 565
                    :.:..:||   .:|.||.    |.|...|:.|:
Zfish   597 --------VPQDTKFI---HTKPNRFEEVAWTRYNQKDQLY 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	157/596 (26%)
		Aes	<117..>233	CDD:223730	52/168 (31%)
nlgn1	XP_017213657.1	COesterase	53..647	CDD:306613	166/626 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575480
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740