Protein Alignment alpha-Est1 and nlgn2b

DIOPT Version :9

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_001159808.1
• Gene: nlgn2b / 100002407
• ZFINID: ZDB-GENE-090918-3
• Length: 860
• Species: Danio rerio
• Alignment Length: 620
• Identity: 168/620 - (27%)
• Similarity: 261/620 - (42%)
• Gaps: 128/620 - (20%)

  Fly    10 LLKMGTKLIGHKIVQYRLGTKQTKVVCTRDGQVRGHRRRTLYDE-----EMYFAFEGIPFAQPPV 69
            ||.:..:|......:..|.|.:..:|.|..|::||.|:. |.:|     |.|.   |:|:|.|||
Zfish    29 LLGLALRLALSSCQRADLTTAKHPMVTTGYGKLRGVRKE-LNNEILGPVEQYL---GVPYATPPV 89

  Fly    70 GELRFRAPQPPHPWLGVRDCT-YPRAKPMQKHFVLS------------------IVEGSEDCLYL 115
            ||.||:.|:.|..|..:|:.| :....|...|.||.                  :...|||||||
Zfish    90 GERRFQPPEAPGSWQEIRNATQFAPVCPQNIHGVLPEIMLPVWFTDNLDAAAAYVQNQSEDCLYL 154

  Fly   116 NVY---------------------SKRLRSDKPLPVIVWIYGGGFQFGEAGRDFYSPDYFMQQDV 159
            |||                     .:.:|..:..||:::|:||.|..| .|..|.:.......:|
Zfish   155 NVYVPTEDGPLTKKHDESSMNRPRDEDIRDRRKKPVMLFIHGGSFMEG-TGNMFDASVLAAYGNV 218

  Fly   160 VVVTFNYRVGALGFLSLADRDLDVPGNAGLKDQVMALRWISQNIAQFNGDPQNITVMGESAGAAS 224
            :|||.|||:|.|||||..|:  ...||.||.||:.||||:::||..|.|||:.||:.|..|||:.
Zfish   219 IVVTMNYRLGVLGFLSSGDQ--SAKGNYGLLDQIQALRWLNENIGHFGGDPERITIFGSGAGASC 281

  Fly   225 VHALMTTEQTRGLFHKAIMQSGSMFCEWANEPSGRWAYR-------LACQLGYSGSENEKEVFRY 282
            |:.|:.:..:.|||.:||.||||....|:..      ||       ||.::|.|.|:. .::...
Zfish   282 VNLLILSHHSEGLFQRAIAQSGSAISSWSVN------YRPLMYTKILAKKVGCSYSDT-ADLVDC 339

  Fly   283 LQKAPASEMAAQGITLVSQEERRQYVLFPFTPVVEPYITRDCVLPRCHREMLPEAWGNDLPLILG 347
            |::....|:..|.:     :..|.::  .|.|||:     ..|:|.....::.:....:..::||
Zfish   340 LRRKSYRELVDQDV-----QPARYHI--AFGPVVD-----GDVVPDDPEILMQQGEFLNYDILLG 392

  Fly   348 GNSFEGLFSYQSTLHDEEHMLSAFEVLIPREIREKSTQSHLKDLLRQ---FKVDNFDDATRGRME 409
            .|..|||........:|....::|:..|...:.........||:||:   |...::.|...|.|.
Zfish   393 VNQGEGLKFVDDNEGEEGISAASFDYTISNFVDNLYGYPEGKDILRETIKFMYTDWADRDNGDMR 457

  Fly   410 FNECLHILSVKHFWHGIHRTVLARLSHAP-ATPTYLYRFDVDSPHFNHFRQVMCGKHVRGVSHAD 473
             .:.|..|...|.|  :...|.....||. .:|.|.|.       |:|..|..........:|.|
Zfish   458 -RKTLLALFTDHQW--VAPAVATAKLHAEFQSPVYFYT-------FHHHCQTEARPEWADAAHGD 512

  Fly   474 DLSYLF-------YHILANKVDKSSMEYQTIQRLVGMWVAFARNDNPNCPQIGPTTWEALDEKGP 531
            ::.|:|       ..:......|:.:....:  ::..|..||:..:||.|
Zfish   513 EIPYVFGVPMVGATELFPCNFSKNDIMLSAV--VMTYWTNFAKTGDPNIP--------------- 560

  Fly   532 QMCLNIGKQLEFIVLPESKQNR----IWDRLYDKN 562
                 :.:..:||   .:|.||    ||.:...|:
Zfish   561 -----VPQDTKFI---HTKPNRFEEVIWTKFSSKD 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	156/575 (27%)
		Aes	<117..>233	CDD:223730	50/136 (37%)
nlgn2b	NP_001159808.1	COesterase	47..611	CDD:278561	164/602 (27%)
		Aes	<181..>279	CDD:223730	44/100 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575523
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740