Protein Alignment alpha-Est2 and Ces2g

DIOPT Version :9

• Sequence 1: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_932116.2
• Gene: Ces2g / 72361
• MGIID: 1919611
• Length: 560
• Species: Mus musculus
• Alignment Length: 566
• Identity: 173/566 - (30%)
• Similarity: 242/566 - (42%)
• Gaps: 144/566 - (25%)

  Fly    17 LVGHKVQQYRLSTGH-----TVILDTKYGQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRA 76
            |:|| ||      ||     :.|..|..|||:|........|.....|.|||:||||||.|||..
Mouse    20 LLGH-VQ------GHDSPETSPIRSTHSGQVQGRLIHVKDTKAGVHTFLGIPFAKPPVGPLRFAP 77

  Fly    77 PQPPEPWQGV-----------LNCTTNRSKPMQRNMLLGIVEGSEDCLHLNVYVKALKSE-KPLP 129
            |:.||||.||           .|.|.|.....:..:.|..|..|||||:||:|..|...| ..||
Mouse    78 PEAPEPWSGVRDGTSQPAICPQNVTMNMEGLKELKLTLPPVSMSEDCLYLNIYTPAHAQEGSNLP 142

  Fly   130 VIVWIYGGGFQKGEASRDIYSPDYF-MKKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQV 193
            |:|||:||....|.||  :|..... ..:.||.|||.|||..|||.|..|.  ...||.|..|||
Mouse   143 VMVWIHGGALTVGMAS--MYDGSVLAATEDVVVVAIQYRLGVLGFFSTGDE--HARGNWGFLDQV 203

  Fly   194 MALRWISQNIAHFNGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESPDN 258
            .||||:.||||||.|:|:.:|:.|||||..||...:.:..::||||:|||:||.||     .|..
Mouse   204 AALRWVQQNIAHFGGNPDRVTIFGESAGGISVSSHVVSPMSKGLFHRAIMESGVAL-----LPGT 263

  Fly   259 NWAF------RLAQNLGYKGDEKDADVLSFLSKVCARQIAAIDQDVINLDEVRSFLLFAFGPVIE 317
            .::|      .:|:..|.:..:.:|.|.....| ...:|.||.         ::|.:.
Mouse   264 IFSFSEVVYQTVAKLSGCEAMDSEALVRCLRGK-SEEEILAIS---------KNFQMI------- 311

  Fly   318 PYETDHCVVPKRHKDLLSEAWGNDIPVIVGGNSFEGLFSYQLVRKDPWALKNFHNILPREVRETS 382
            |...|...:||..::||:.|..:.:|.|:|.|:.|                 :..|:|:.:..|.
Mouse   312 PGVVDGEFLPKHPQELLASADFHPVPSIIGFNNDE-----------------YGWIVPKVIGSTQ 359

  Fly   383 SLEG-----------------------QDLLVR---------RLKQLYFNNEMQESMEMFEALNI 415
            :::|                       .|||:.         :..|:.|...|::.|.:..:|.:
Mouse   360 TIKGITRENLQAVLKDTAPQMMLPPECSDLLMEEYMEDIEDPKTLQIQFTEMMEDFMFVIPSLQV 424

  Fly   416 FSHRQIWHDTHRFILARQSYAPKTPTYLYRFDFDS--------PHFNQFRRLVCGDRIRGVAHAD 472
                         ...::|:|   |.|.|.|...|        ||.|             ..|.|
Mouse   425 -------------AYFQRSHA---PVYFYEFQHQSSFLKDVRPPHVN-------------ADHGD 460

  Fly   473 ELSYLFYNII-ASKLDKSSMEYKTIERMVGMWTSFASSGNPNCPEL 517
            |:.::|.:.. ..||:.:..|.....||:..|.:||..||||...|
Mouse   461 EVPFVFGSFFWGMKLNLTEEEKLLNRRMMKYWANFARHGNPNSESL 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	166/546 (30%)
		Aes	<117..>221	CDD:223730	50/105 (48%)
Ces2g	NP_932116.2	COesterase	31..539	CDD:278561	166/548 (30%)
		Aes	72..>337	CDD:223730	105/290 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832734
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.640