Protein Alignment alpha-Est2 and Ces2el1

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001418901.1
• Gene: Ces2el1 / 688542
• RGDID: 1587637
• Length: 559
• Species: Rattus norvegicus
• Alignment Length: 530
• Identity: 166/530 - (31%)
• Similarity: 241/530 - (45%)
• Gaps: 95/530 - (17%)

  Fly    34 ILDTKYGQVRGLQRKTVYDKE---PYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTTNRSK 95
            |.:|..|||||   ..|:.|:   ....|.|||:||||||.|||..|:.||||.||.:.|::.:.
  Rat    33 IRNTHTGQVRG---SLVHVKDTDIDVHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDATSHPAM 94

  Fly    96 PMQRNMLLGI------------VEGSEDCLHLNVYVKALKSE-KPLPVIVWIYGGGFQKGEASRD 147
            .:|.:.::|.            :..|||||:||:|......| ..|||:|||:||....|.||
  Rat    95 CLQNDNMMGSEDMKIMKLILPPISMSEDCLYLNIYAPTHAHEGSNLPVMVWIHGGALTVGMAS-- 157

  Fly   148 IYSPDYF-MKKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPN 211
            :|..... ..:.||.|.|.|||..|||.|..|.  ...||.|..|||.||||:.||||||.|:||
  Rat   158 MYDGSMLAATEDVVVVTIQYRLGVLGFFSTGDE--HARGNWGYLDQVAALRWVQQNIAHFGGNPN 220

  Fly   212 NITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESPDNNWAFRLAQNLGYKGDEKD 276
            .:|:.|||||..||...:.:..::||||.|||:||..:...:.|..:...:|:..||     ...
  Rat   221 RVTIFGESAGGTSVSSHVVSPMSQGLFHGAIMESGVVVLPDLISRSSEMVYRIVANL-----SGC 280

  Fly   277 ADVLSFLSKVCARQIAAIDQDVINLDEVRSFLLFAFGPVIEPYETDHCVVPKRHKDLLSEAWGND 341
            |.|.|.....|.|  ...:.:::::::|...:         |...|...:||..::||:.|..:.
  Rat   281 AAVDSETLMQCLR--GKSEAEILDINKVFKII---------PAVVDGEFLPKHPQELLASANFHR 334

  Fly   342 IPVIVGGNSFE------GLFS-----YQLVRKD-PWALKN--FHNILPREVRETSSLEGQDLLVR 392
            :|.|:|.|:.|      .:|.     .::.||. |..||:  ...:||.|.        .|||:.
  Rat   335 VPSIIGINNDEYGWILPMIFDSAQKIEEITRKTLPTVLKSTALKMMLPPEC--------GDLLME 391

  Fly   393 ---------RLKQLYFNNEMQESMEMFEALNIFSHRQIWHDTHRFILARQSYAPKTPTYLYRFDF 448
                     :..|..|...|.:.|.:..||.: :|.|..|               .|.|.|.|.
  Rat   392 EYMGDTEDPKTLQAQFREMMGDFMFVIPALQV-AHFQRSH---------------APVYFYEFQ- 439

  Fly   449 DSPHFNQFRRLVCGDRIRGVAHADELSYLFYNIIAS-KLDKSSMEYKTIERMVGMWTSFASSGNP 512
               |.:.|.:.|....:: ..|.||:..:|..::.. |...:..|.....:::..|.:||..|||
  Rat   440 ---HRSSFFKDVKPPHVK-ADHGDEVFLVFGYLVGDIKFPHTEEEELLSRKIMKYWANFARHGNP 500

  Fly   513 NCPELGSAKW 522
            |..  |...|
  Rat   501 NSE--GLPHW 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	166/530 (31%)
Ces2el1	NP_001418901.1	COesterase	30..538	CDD:395084	166/530 (31%)