Protein Alignment alpha-Est2 and Ces5a

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001368779.1
• Gene: Ces5a / 67935
• MGIID: 1915185
• Length: 579
• Species: Mus musculus
• Alignment Length: 549
• Identity: 166/549 - (30%)
• Similarity: 252/549 - (45%)
• Gaps: 89/549 - (16%)

  Fly    37 TKYGQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTTNRSKPMQ--- 98
            ||.|.|:|.|...:...||...|.|||:|.||:|.|||..||||.||..:...|...:...|
Mouse    39 TKLGWVQGKQATVLGRLEPVNVFLGIPFAAPPLGPLRFSKPQPPIPWDNLREATAYPNLCFQNLE 103

  Fly    99 -----RNML------LGIVEGSEDCLHLNVYVKA-LKSEKPLPVIVWIYGGGFQKGEASRDIYSP 151
                 :|:|      ||:   |||||:||:|... ..:...|||:|||.||||:.|.||  |:..
Mouse   104 WLFIYQNLLKVSYPILGM---SEDCLYLNIYAPCHANNGSSLPVMVWIPGGGFETGSAS--IFDG 163

  Fly   152 DYF-MKKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITL 215
            ... :.:.|:.|.|.|||...||.:.::.  ..|||....||:.||.|:.:||.:|.|:|:::|:
Mouse   164 SALAVYEDVLVVTIQYRLGIFGFFTTQNQ--HAPGNWAFWDQLAALLWVRENIKYFGGNPDSVTI 226

  Fly   216 MGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESPDNNWAFRLAQNLGYKGDEKDADVL 280
            .|.|||:.|:..::.:..:..|||:||||||.|:...::|.||:    |..:|....:..|.:|.
Mouse   227 FGNSAGAISISSLILSPLSADLFHRAIMQSGVAIIPSLKSSDND----LKHDLQVVANVCDCNVS 287

  Fly   281 SFLSKV---CARQIAAIDQDVINLDE-VRSFLLFAFGPVI--EPYETDHCVVPKRHKDLLSEAWG 339
            .  ||.   |.|:.:::  ::::|.: .:||.....|...  ||.|            |||:...
Mouse   288 D--SKALLKCLREKSSL--ELMSLSQKAKSFTRVVDGSFFSEEPLE------------LLSQKTL 336

  Fly   340 NDIPVIVGGNSFEGLFSYQL-VRKDP---------WALKNFHNILPREVRETSSLEGQDLLVRRL 394
            ..:|.|:|.|:.|  ..|.| ||..|         .||...|.:|        .:..|.|.:  :
Mouse   337 KIVPSIIGVNNQE--CGYILPVRDTPEILLGSNESTALTLIHTLL--------HIPTQHLYI--V 389

  Fly   395 KQLYFNNEMQESMEMFEALNIFSHRQIWHDTHRFILARQSYAPKTPTYLYRFDFDSPHFNQFRR- 458
            .:.||:.:...:......|::|.  .::......:.||.......|.|.|.|. ..||..|..|
Mouse   390 TKEYFHGKHSPTDIRDTLLDLFG--DVFFVVPGLVTARYHRDSGGPVYFYEFQ-HRPHCFQNSRP 451

  Fly   459 -LVCGDRIRGVAHADELSYLFYNIIAS----KLDKSSMEYKTIER-MVGMWTSFASSGNPNCPEL 517
             .|..|      |.||:.::|......    ..::::.|.|.:.| |:..|.:||.||:||..:|
Mouse   452 AFVKAD------HTDEIRFVFGGPFLKGDVVMFEEATEEEKLLSRKMMKYWANFARSGDPNGADL 510

  Fly   518 GSAKWEAVQLKENAVEKCFNISHDLEMRD 546
              ..|......|..:|...|||....::|
Mouse   511 --PPWPVYDENEQYLELDVNISTGRRLKD 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	166/549 (30%)
Ces5a	NP_001368779.1	COesterase	33..543	CDD:395084	166/549 (30%)