Protein Alignment alpha-Est2 and Aadac

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_075872.1
• Gene: Aadac / 67758
• MGIID: 1915008
• Length: 398
• Species: Mus musculus
• Alignment Length: 295
• Identity: 64/295 - (21%)
• Similarity: 106/295 - (35%)
• Gaps: 98/295 - (33%)

  Fly   105 IVEGSEDCLHLNVYVKALKSEKPLPVIVWIYGGGFQKGEA---SRDIYSPDYFMKKPVVFVAINY 166
            ::|.:.|.:.:.:|:...||......:.:|:|||:..|.|   |.|..|.....|...|.|:.:|
Mouse    80 VMETAFDSVPVRIYIPKRKSMALRRGLFYIHGGGWCLGSAAHFSYDTLSRWTAHKLDAVVVSTDY 144

  Fly   167 RLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQN--IAHFNGDPNNITLMGESAGSASVHVMM 229
            .||         ||...|..  .:|...:|||..|.  :..:..||..:.:.|:|||
Mouse   145 GLA---------PKHHFPRQ--FEDVYRSLRWFLQEDVLEKYGVDPRRVGVSGDSAG-------- 190

  Fly   230 TTEQTRGLFHKAIMQSGCALSEWVESPDNNWAFRLAQNLGYKGDEKDADVLSFLSKVCARQIAAI 294
                  |....|:.|      :.::.||.....:: |.|.|..                  :.|:
Mouse   191 ------GNLAAAVTQ------QLIQDPDVKIKLKV-QALIYPA------------------LQAL 224

  Fly   295 DQDVINLDE-------VRSFLL------FAFGPVIE---------PYETDH--------CVVPKR 329
            |.:|.:..|       .||.::      |.....:|         |.|:.|        .::|:|
Mouse   225 DTNVPSQQEGSHFPVLTRSLMVRFWSEYFTTDRGLEKAMLLNQHVPMESSHLLQFVNWSSLLPER 289

  Fly   330 HKDLLSEAWGNDIPVIVGGNSFEGLFSYQLVRKDP 364
            :|.  |..:.|..|    |:|       :|.:|.|
Mouse   290 YKK--SPVYKNPTP----GSS-------ELAQKYP 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	64/295 (22%)
Aadac	NP_075872.1	Abhydrolase_3	106..356	CDD:400284	59/269 (22%)
		Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3	110..112		0/1 (0%)