Protein Alignment alpha-Est2 and tg

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001316794.1
• Gene: tg / 567631
• ZFINID: ZDB-GENE-030519-1
• Length: 2733
• Species: Danio rerio
• Alignment Length: 613
• Identity: 165/613 - (26%)
• Similarity: 252/613 - (41%)
• Gaps: 146/613 - (23%)

  Fly    11 IKMGAQLVGHKVQQYRLSTGHTVILDTKYGQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFR 75
            |:.|.||   :.....:....|::.:::...:.|...|.|    .||.  |:|||:||:|||||.
Zfish  2155 IRTGVQL---EFTSVSIPDHGTLLGESEVKPITGSDSKRV----TYFL--GVPYARPPIGDLRFS 2210

  Fly    76 APQPPEPWQGVLNCTTNRSKPMQRNMLLGIVEGSEDCLHLNVYVKALKSEKPLPVIVWIYGGGFQ 140
            .|||.: |.|..|.|..||..:|...|.. ...|||||:|||:| |....|..||:|:.:..|
Zfish  2211 PPQPAD-WTGTWNATFFRSSCLQPGDLTD-SSSSEDCLYLNVFV-ASSVAKNAPVLVFFHNSG-- 2270

  Fly   141 KGEASRDIYSPDYFMK-KPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIA 204
                 .|:....|... ..::.|..::|:||.||||.....|  |||.||:||..||.|:.:|||
Zfish  2271 -----SDLLDGSYLAAVGNIIVVTASFRMAAFGFLSAGSSAL--PGNYGLQDQAAALGWVQKNIA 2328

  Fly   205 HFNGDPNNITLMGESAGS--ASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESPDNNWAFRLAQN 267
            .|.|||..:|:..|..|:  ||:|  :|:.....||.:|::..|...|..|....:. |.....:
Zfish  2329 LFGGDPTKVTVGAERNGADIASLH--LTSPSASSLFSRALLMGGSVFSPAVVMSSSK-AQAQTSS 2390

  Fly   268 LGYKGDEKDADVLSFLSKVCARQIAAIDQDVINLDEVRSFLLFAFGPVIEPYETDHCVVPKRHKD 332
            |..:.|.:.||....|.  |.|     .:...:::..::.||...||:
Zfish  2391 LARELDCQAADPSQLLD--CLR-----SKPAHSINAAQTKLLAVSGPL----------------- 2431

  Fly   333 LLSEAWGNDIPVIVG-----------------------GNSFE-GLFSYQLVRKDPWALKNFHNI 373
               :||.   ||:.|                       |:||| ||.|.   .|:   :|||..:
Zfish  2432 ---QAWS---PVVDGNVVREMPSVALQSGRFHKAEILLGSSFEDGLISR---AKN---IKNFEQL 2484

  Fly   374 LPREVRET-------SSLEGQDLLVRRLKQLYFNNEMQESMEMFEAL---------NIFSHRQIW 422
            ..|...:|       :||.|.|.          |..::|:...|.:|         |:|| |.:.
Zfish  2485 QGRADSKTAFYAALSNSLGGDDA----------NAFVKEAATWFYSLQHSPTPSGYNVFS-RALE 2538

  Fly   423 HDTH-RFILA-----RQSYAPKTPTYLYRFDF-DSPHFNQFRRLVCGDRIRGVAHADELSYLF-Y 479
            :.|. .||:.     .:.:|..|.|.:|.:.. ::..:|.....|..|          :.||| .
Zfish  2539 NATRDLFIICPTVDMAEFWAANTQTGVYMYHLPENAAYNSVDLSVPMD----------VQYLFGV 2593

  Fly   480 NIIASKLDKSSMEYKTIE-RMVGMWTSFASSGNPNCPELGS--------AKWEAVQLKENAVEKC 535
            .:.|.:.|..|.:.||.. :::....:|..|||||.|...|        ..|.  |...:...:.
Zfish  2594 PLAAEQRDLFSYKEKTFTLQIMNYMANFIKSGNPNLPLAASRTSFGKFLPPWP--QFMPHVGGRA 2656

  Fly   536 F-NISHDL-EMRDLPESDCLAVWDTFYP 561
            : .:|..| ..::|..|.| :.|..:.|
Zfish  2657 YKELSSTLVNRKNLQRSQC-SFWSQYVP 2683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	158/583 (27%)
tg	NP_001316794.1	Thyroglobulin_1	40..98	CDD:459665
		Thyroglobulin_1	102..161	CDD:459665
		TY	165..249	CDD:469630
		TY	301..358	CDD:238114
		TY	<594..639	CDD:238114
		Thyroglobulin_1	643..705	CDD:459665
		TY	990..1047	CDD:238114
		TY	1133..1194	CDD:469630
		Ephrin_rec_like	1425..1470	CDD:429604
		COesterase	2172..2678	CDD:395084	159/586 (27%)