Protein Alignment alpha-Est2 and nlgn3b

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: XP_005165239.1
• Gene: nlgn3b / 567415
• ZFINID: ZDB-GENE-060526-197
• Length: 846
• Species: Danio rerio
• Alignment Length: 607
• Identity: 157/607 - (25%)
• Similarity: 260/607 - (42%)
• Gaps: 141/607 - (23%)

  Fly    35 LDTKYGQVRGLQRKTVYD-KEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTTNRSKPM- 97
            ::|..|::||::.....: ..|...:.|:|||.||||:.||..|..|..|.||.|.|  |..|:
Zfish    48 VNTALGRLRGMRVAVATEGLGPVDQYLGVPYAAPPVGEKRFMPPDAPSAWSGVRNAT--RFPPVC 110

  Fly    98 ---QRNMLLGIV-----------------EGSEDCLHLNVYVKALKSEK---------------- 126
               .||.:..|:                 |.|||||::|:||......|
Zfish   111 PQTVRNAVPDIMMPVWATYNMDTVATYLQEQSEDCLYMNIYVPTQSGTKRTGDMSADTERTEDDG 175

  Fly   127 -------PLPVIVWIYGGGFQKGEASRDIYSPDYFMK-KPVVFVAINYRLAALGFLSLKDPKLDV 183
                   |.||:::|:||.:.:|  :.:|........ ..|:.:.:|||:..|||||..|..  .
Zfish   176 LRDSRDDPRPVMLFIHGGSYMEG--TGNIMDGSVLASYGNVIVITLNYRVGILGFLSTGDQA--A 236

  Fly   184 PGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCA 248
            .||.||.||:.|||||::||.:|.|||..:|:.|...|::.|.::..:..:.||||:||:|||.|
Zfish   237 KGNYGLLDQIQALRWINKNIGYFGGDPGRVTVFGSGIGASCVSLLTLSHHSEGLFHRAIIQSGSA 301

  Fly   249 LSEW-VESPDNNWAFRLAQNLGYKGDEKDADVLSFLSKVCARQIAAIDQDVINLDEVRSFLLFAF 312
            ||.| |......:...||:.:|....:.. |::..:.|...|::  ::|::    :...|.: ||
Zfish   302 LSSWSVNYQPVKYTRLLAERVGCNVLDTQ-DLVLCMQKRSYREL--VEQEI----QPARFHV-AF 358

  Fly   313 GPVIEPYETDHCVVPKRHKDLLSEAWGNDIPVIVGGNSFEGL-FSYQLVRKD---------PWAL 367
            ||||     |..::|...:.|:.:....:..:::|.|..||. |...:|..:         .:.:
Zfish   359 GPVI-----DGDLIPDDPEVLMEQGEFLNYDIMLGVNQGEGFRFVEGVVEPEEGGVSGSDFDFTV 418

  Fly   368 KNFHNIL---PREVRETSSLEGQDLLVRRLKQLYFNNEMQESMEMFE--ALNIFSHRQ------I 421
            .:|.:.|   |         ||:|.|...:|.:|.:...:::.|...  .:.:|:..|      :
Zfish   419 SDFVDSLYGYP---------EGKDTLRETIKFMYTDWADRDNPETRRKTLVAMFTDHQWVEPAVV 474

  Fly   422 WHDTHRFILARQSYAPKTPTYLYRFDFDSPHFNQFRRLVCGDRIRGVAHADELSYLF-------Y 479
            ..|.|    ||..    :||:.|.|   ..|.....:....|.    ||.|||.|:|       .
Zfish   475 TADLH----ARYG----SPTFFYAF---YHHCQSPMKPPWADS----AHGDELPYVFGVPLIGPT 524

  Fly   480 NIIASKLDKSSMEYKTIERMVGMWTSFASSGNPNCPELGSAKWEAVQLKENAVEKCFNISHDLEM 544
            .:......::.:....:  ::..||:||.:|:||.|.....|:  :..|.|..|:
Zfish   525 ELFPCNFSRNDIMLSAV--VMTYWTNFAKTGDPNKPVPQDTKF--IHTKANRFEE---------- 575

  Fly   545 RDLPESDCLAVWDTFYPRESLF 566
                     ..|..:.|.:.|:
Zfish   576 ---------VTWAKYGPHDQLY 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	154/595 (26%)
nlgn3b	XP_005165239.1	COesterase	45..609	CDD:395084	157/607 (26%)
		Herpes_BLLF1	<753..>843	CDD:282904