Protein Alignment alpha-Est2 and ces2a

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001070720.1
• Gene: ces2a / 566132
• ZFINID: ZDB-GENE-061013-99
• Length: 555
• Species: Danio rerio
• Alignment Length: 574
• Identity: 158/574 - (27%)
• Similarity: 247/574 - (43%)
• Gaps: 134/574 - (23%)

  Fly    29 TGHTVILDTKYGQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTTNR 93
            :|...:|  |:|.|||...|..........:.|||:|:||||..|..||||.:.|:|:.|.|.:.
Zfish    25 SGPVAVL--KHGSVRGQYVKAKGSPAVVEQYLGIPFAQPPVGPHRLAAPQPVQGWEGIRNATEHP 87

  Fly    94 SKPMQR-NMLLGIVEG----------SEDCLHLNVYVKALKSE-KPLPVIVWIYGGGFQKGEAS- 145
            ...:|. ::|..|.:.          |||||:||||..:.::| :.|||::||:|||...|.|.
Zfish    88 LMCLQNPDILPAIAKAIDLEVTAIGVSEDCLYLNVYTPSQRAESEKLPVMIWIHGGGLAMGGACM 152

  Fly   146 -RDIYSPD------YFMKKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNI 203
             :::...|      |   :.||.|.|.|||..||:.|..|.  ...||.|..||:.||:|:.|||
Zfish   153 FKELCLYDGTPLAAY---EKVVVVVIQYRLGILGYFSTGDQ--HAKGNWGFLDQIAALQWVQQNI 212

  Fly   204 AHFNGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSE--WVESPDNNWAFRLAQ 266
            ..|.|||.::|:.|||||..|..::..:..|:|||.:||.|||.|..:  :|:.|..:  .::..
Zfish   213 EAFGGDPQSVTIAGESAGGISASLLTLSPMTKGLFQRAIFQSGVATVKGYFVKDPSTH--AQVIA 275

  Fly   267 NLGYKGDEKDADVLSFLSKVCARQIAAIDQDVINLDEVRSFLLFAFGPVIEPYETDHCVVPKRHK 331
            |:    .|.|......|.| |.|::.  ::.:|...:.:.  :|....|      |...:..:.:
Zfish   276 NI----TECDFSSSEVLVK-CIREMT--EEQIIKAAQKKG--IFPGAAV------DGEFIKAQPE 325

  Fly   332 DLLSEAWGNDIPVIVGGNSFEGLFSYQLVRKDPWALKNFHNILPRE-VRETSSLEGQDLLVRRLK 395
            ::|.......:|:::|..:.|  |.        |.|...  .||:| |:...:...:|    ||.
Zfish   326 EILKSKDFQKVPILIGTTNHE--FG--------WMLPQI--FLPKEWVKGMDTKAAKD----RLG 374

  Fly   396 QL---------------YFNNEM--QESMEMFEAL--NIFS----------HRQIWHDTHRFILA 431
            .|               ||.|..  :|..:.|..|  :||.          ||:
Zfish   375 LLNADGASGANGIIADEYFKNAKTPEEIRDAFTELLGDIFMVIPSITVASYHRE----------- 428

  Fly   432 RQSYAPKTPTYLYRFDFDSPHFNQFR-RLVCGDRIRGVAHADELSYL----FYNIIASKLDKSSM 491
                 ...|.|:|.|.......|:|| ..|..|      |||::.::    |:::....|...:.
Zfish   429 -----AGVPVYMYEFQHGPSTANKFRPSFVKAD------HADDVGFVFGACFWDVHVKGLGTLTE 482

  Fly   492 EYKTIERMVGMW-TSFASSGNPN-CP-------------ELGSAKWEAVQLKEN 530
            |...:.|.|..: .:|..:|:|| .|             .||..:.|...||::
Zfish   483 EENQLCRTVMKYRANFIRTGSPNPAPVPWPVYDQSNKYLNLGLQQTEGQDLKKD 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	157/569 (28%)
ces2a	NP_001070720.1	COesterase	25..541	CDD:395084	158/574 (28%)