Protein Alignment alpha-Est2 and nlgn3a

DIOPT Version :9

• Sequence 1: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: XP_005157256.1
• Gene: nlgn3a / 562702
• ZFINID: ZDB-GENE-071219-1
• Length: 878
• Species: Danio rerio
• Alignment Length: 626
• Identity: 171/626 - (27%)
• Similarity: 269/626 - (42%)
• Gaps: 150/626 - (23%)

  Fly    30 GHTVILDTKYGQVRGLQRKTVYDK--EPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLN---- 88
            |:...::|:||::|| .|..::.:  .|...:.|:|||.||||:.||..|:||..|.|:.|
Zfish    66 GYYPTVNTQYGKLRG-ARVPLHSEILGPVDQYLGVPYATPPVGEKRFLPPEPPSSWSGIKNATHF 129

  Fly    89 ---CTTNRSKPMQRNML-------LGIV-----EGSEDCLHLNVY-----VKALKSE---KP--- 127
               |..|....:...|:       |.||     :.:||||:||:|     ||.:..|   ||
Zfish   130 APVCPQNIHNAVPEIMMPIWFTFNLDIVATSIQDQNEDCLYLNIYVPTEDVKRISKECTRKPNKK 194

  Fly   128 --------------------------------LPVIVWIYGGGFQKGEASRDIYSPDYFMKKPVV 160
                                            .||:|:|:||.:.:|..:. |..........|:
Zfish   195 ICRKGGTHSKKQGEDLSDNDGDEDEDIRDTGAKPVMVYIHGGSYMEGTGNM-IDGSVLASYGNVI 258

  Fly   161 FVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSASV 225
            .:.:|:|:..|||||..|..  ..||.||.||:.||||||:||.:|.||.|.||:.|...|::.|
Zfish   259 VITLNFRVGVLGFLSTGDQA--AKGNYGLLDQIQALRWISENIGYFGGDSNRITVFGSGIGASCV 321

  Fly   226 HVMMTTEQTRGLFHKAIMQSGCALSEW-VESPDNNWAFRLAQNLGYKGDEKDADVLSFLSKV-CA 288
            .::..:..:.||||:||:|||.|||.| |......:...||:.:|       .:||..|..| |.
Zfish   322 SLLTLSHHSEGLFHRAIIQSGSALSSWAVNYQPVKYTRLLAEKVG-------CNVLDTLDMVDCL 379

  Fly   289 RQIAA---IDQDVINLDEVRSFLLFAFGPVIEPYETDHCVVPKRHKDLLSEAWGNDIPVIVGGNS 350
            |:.:|   ::||:   ...|..:  ||||||     |..|:|...:.|:.:....:..:::|.|.
Zfish   380 RKKSARELVEQDI---QPARYHV--AFGPVI-----DGDVIPDDPEILMEQGEFLNYDIMLGVNQ 434

  Fly   351 FEGL-FSYQLVRKDPWALKNFHNILPREVRETSSL----EGQDLLVRRLKQLYFNNEMQESMEMF 410
            .||| |...:|..:.....|..:....:.  ..||    ||:|.|...:|.:|.:...:::.|..
Zfish   435 GEGLRFVENVVDSEDGVSGNDFDFSVSDF--VDSLYGYPEGKDTLRETIKFMYTDWADRDNPETR 497

  Fly   411 E--ALNIFSHRQ------IWHDTHRFILARQSYAPKTPTYLYRFDFDSPHFNQFRRLVCGDRIRG 467
            .  .:.:|:..|      :..|.|    ||..    :|||.|.|   ..|.....:....|
Zfish   498 RKTLVALFTDHQWVEPSVVTADLH----ARYG----SPTYFYAF---YHHCQSLMKPAWSD---- 547

  Fly   468 VAHADELSYLF-------YNIIASKLDKSSMEYKTIERMVGMWTSFASSGNPNCPELGSAKWEAV 525
            .||.||:.|:|       .::......|:.:....:  ::..||:||.:|:||.|.....|:  :
Zfish   548 AAHGDEVPYVFGIPMIGPTDLFPCNFSKNDIMLSAV--VMTYWTNFAKTGDPNKPVPQDTKF--I 608

  Fly   526 QLKENAVEKCFNISHDLEMRDLPESDCLAVWDTFYPRESLF 566
            ..|.|..|:                   ..|..:.|::.|:
Zfish   609 HTKANRFEE-------------------VAWSKYNPQDQLY 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	164/579 (28%)
		Aes	<117..>221	CDD:223730	44/146 (30%)
nlgn3a	XP_005157256.1	COesterase	69..651	CDD:306613	170/623 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575376
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840