Protein Alignment alpha-Est2 and ces3

DIOPT Version :9

• Sequence 1: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001038401.1
• Gene: ces3 / 560651
• ZFINID: ZDB-GENE-030131-9563
• Length: 549
• Species: Danio rerio
• Alignment Length: 541
• Identity: 151/541 - (27%)
• Similarity: 232/541 - (42%)
• Gaps: 122/541 - (22%)

  Fly    29 TGHTVILDTKYGQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTTNR 93
            :|..|:|  |:|.|||...|..........:.|||:|:||||..|..||||.:.|:|:.|.|...
Zfish    25 SGPVVVL--KHGSVRGQYVKAKGSPAVVEQYLGIPFAQPPVGPHRLAAPQPVQGWEGIRNATEYS 87

  Fly    94 SKPMQ---------RNMLL-----GIVEGSEDCLHLNVYVKALKSEK-PLPVIVWIYGGGFQKGE 143
            |..:|         ::|.|     |:   |||||:||||..:.:||. ..||:|||:||....|.
Zfish    88 SMCLQDPNIVPKYAKSMTLELPPTGV---SEDCLYLNVYTPSQRSESDKFPVMVWIHGGALVIGG 149

  Fly   144 ASRDIYSPDYFMKKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNG 208
            |.....:|....:| ||.|.|.|||..||:||..|.  ...||.|..||:.||:|:.|||..|.|
Zfish   150 ACMYDGTPLAAYEK-VVVVVIQYRLGILGYLSTGDQ--HAQGNWGFLDQIAALQWVQQNIEAFGG 211

  Fly   209 DPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESPDNNWAFRLAQNLGYKGD 273
            ||.::|:.|||||..|..::..:..|:|||.:||.|||.|..:.....|.....::..|:    .
Zfish   212 DPQSVTIAGESAGGISASLLTLSPMTKGLFQRAIFQSGVATVKGYSFKDPLTYAKVIANI----T 272

  Fly   274 EKDADVLSFLSKVCARQIAAIDQDVINLDEVRSFLLFAFGPVIEPYET-DHCVVPKRHKDLLSEA 337
            |.|......|.| |.|::.  ::.:|...:.:..|         |..| |...:..:.:::|...
Zfish   273 ECDFSSSEVLVK-CIREMT--EEQIIKAAQKKYRL---------PGATVDGEFIKAQPEEILKSK 325

  Fly   338 WGNDIPVIVG--GNSFEGLFSYQLVRKDPWA-----------LKNFHNI---------------- 373
            ....||::||  .:.|....|:.::.|| ||           |..|:|.
Zfish   326 DFPKIPILVGTTNHEFGWTLSHAILPKD-WAKGMDAKSAKQTLDFFYNAGASEANGIIADEYFKN 389

  Fly   374 --LPREVRETSSLEGQDLLVRRLKQLYFNNEMQESMEMFEALNIFSHRQIWHDTHRFILARQSYA 436
              .|.|:|:.                 |...:.:.:.:..::.:.|:       ||...|
Zfish   390 AKTPEEIRDA-----------------FTELLGDIIMVIPSIKVASY-------HRDAGA----- 425

  Fly   437 PKTPTYLYRFDFDSPHFNQFR-RLVCGDRIRGVAHADELSYLF--------YNIIASKLDKSSME 492
               |.|:|.|.......|:|| ..|..|      |.||:.::|        ..:..:..::.:..
Zfish   426 ---PVYMYEFQHGPSIANKFRPSFVKAD------HGDEIGFMFGACFWDGQVKVTGTLTEEENQL 481

  Fly   493 YKTIERMVGMWTSFASSGNPN 513
            .:|:.:   .|.:|..:|:||
Zfish   482 CRTVMK---YWANFVRTGSPN 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	150/538 (28%)
		Aes	<117..>221	CDD:223730	46/104 (44%)
ces3	NP_001038401.1	COesterase	24..535	CDD:278561	151/541 (28%)
		Aes	<122..>235	CDD:223730	49/115 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575338
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.740