Protein Alignment alpha-Est2 and Ces2h

DIOPT Version :9

• Sequence 1: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001258974.1
• Gene: Ces2h / 436059
• MGIID: 3648740
• Length: 558
• Species: Mus musculus
• Alignment Length: 528
• Identity: 166/528 - (31%)
• Similarity: 247/528 - (46%)
• Gaps: 100/528 - (18%)

  Fly    27 LSTGHTVILDTKYGQVRGLQRKTVYDKE---PYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLN 88
            :.|.||       ||:.|   ..::.|:   ...:|.|||:||||||.|||..|:|||||.||.:
Mouse    32 IRTTHT-------GQILG---SLIHMKDLDVGVHSFLGIPFAKPPVGPLRFAPPEPPEPWGGVRD 86

  Fly    89 CTTNRSKPMQ----RNM----LLGIV----EGSEDCLHLNVYVKALKSE-KPLPVIVWIYGGGFQ 140
            .|::.:..:|    .||    ||.:.    ..|||||:||:|......| ..|||:|||:||...
Mouse    87 GTSHPAMCLQDITAMNMQAFKLLKLTLPPFPMSEDCLYLNIYAPDHAHEGSNLPVMVWIHGGSLV 151

  Fly   141 KGEASRDIYSPDYF-MKKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIA 204
            .|.||  :|..... ..:.||.|.|.|||..|||.|..|.:  ..||.|..|||.||||:.||||
Mouse   152 IGMAS--MYDGSMLAAMENVVVVTIQYRLGVLGFFSTGDER--ARGNWGYLDQVAALRWLQQNIA 212

  Fly   205 HFNGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESPDNNWAFRLAQNLG 269
            :|.|:|:.:|:.|.|||..||..::.:..::|||..|||:||.||...:.|..::..::...||
Mouse   213 YFGGNPDRVTIFGTSAGGTSVSSLVVSPMSQGLFRGAIMESGVALISSLISVSSDVVYQTVANL- 276

  Fly   270 YKGDEK-DADVL-SFLSKVCARQIAAIDQDVINLDEVRSFLLFAFGPVIEPYETDHCVVPKRHKD 332
             .|.|: |::.| :.|......:|.||::              ||  .|.|...|...:|:..::
Mouse   277 -SGCEQVDSEALVNCLRGKSEEEIMAINK--------------AF--KIIPGIVDGIFLPRHPQE 324

  Fly   333 LLSEAWGNDIPVIVGGNSFEGLFSYQLVRKDPWALKNFHNILPREVRETSSLEGQD------LLV 391
            |::.|..:.:|.|:|.|:.|                 :..|:|..:....|.:|.|      :|.
Mouse   325 LMASADFHPVPSIIGVNNDE-----------------YGWIIPSSMSMIDSKKGMDRQMVQAILQ 372

  Fly   392 RRLKQLYFNNE-----MQESM---EMFEALNIFSHRQIWHDTHRFILARQ------SYAPKTPTY 442
            ||..|:.:..|     |:|.|   |..:.|.: ..:::..|....|.|.|      |:|   |.:
Mouse   373 RRATQMMWPPEVSDLLMEEYMGDNEDPQFLQV-QFKEMMKDFTFVIPALQVAQFQRSHA---PVF 433

  Fly   443 LYRFDFDSPHFNQFR-RLVCGDRIRGVAHADELSYLFYNII-ASKLDKSSMEYKTIERMVGMWTS 505
            .|.|......|...: ..|..|      |.||:.::|.:.. .:::|.:..|.....||:..|.:
Mouse   434 FYEFQHRPSFFKDSKPSHVKAD------HGDEILFIFRSFWGGTQVDFTEEEELLSRRMMKYWAN 492

  Fly   506 FASSGNPN 513
            ||...|||
Mouse   493 FARQRNPN 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	164/523 (31%)
		Aes	<117..>221	CDD:223730	46/105 (44%)
Ces2h	NP_001258974.1	COesterase	30..537	CDD:278561	166/528 (31%)
		Aes	<127..>230	CDD:223730	47/106 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832873
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.640