Protein Alignment alpha-Est2 and Nlg4

DIOPT Version :9

• Sequence 1: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Alignment Length: 660
• Identity: 167/660 - (25%)
• Similarity: 253/660 - (38%)
• Gaps: 222/660 - (33%)

  Fly    11 IKMGAQLVGHKVQQYRLSTGHTVILDTKYGQVRGLQRKTVYDKEPY------FAFEGIPYAKPPV 69
            |..||:| ||::.|            |:||::.||    :...:.:      ..|.|:|||.||.
  Fly    33 IYKGARL-GHRIVQ------------TRYGRLHGL----ILPLDSFRFLRSVEVFLGVPYATPPT 80

  Fly    70 GDLRFRAPQPPEPWQGV-------------LNCTTNRSKPMQR---------NMLLGIVEG-SED 111
            ...||...:.|.||.|:             |....|.:..:::         ..||..:|. |||
  Fly    81 KQNRFSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSED 145

  Fly   112 CLHLNVY--VKALKSEKPLPVIVWIYGGGFQKGEASRDIYSPDYFMK-KPVVFVAINYRLAALGF 173
            ||:|||:  |.|..:||.|||||:|:|..|:  .:|.:.|....... ..||.|.:||||..|||
  Fly   146 CLYLNVFSPVNAGANEKKLPVIVFIHGESFE--WSSGNPYDGSVLASYGEVVVVTLNYRLGILGF 208

  Fly   174 LSLK-DPKLDV-PGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSASVHVMMTT-EQTR 235
            |:.. :|.... ..|.||.||:.||.||.|||..|.||||::||.|...|:|.::.:||: ...|
  Fly   209 LNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVR 273

  Fly   236 GLFHKAIMQSGCALSEW--VESPDNNWAFRLAQNLG-------YKGDEKDADVLSFLSKVCARQI 291
            ||||:||:.||.|.|.|  ||.| ..:|.:||:.:.       .:..|:..|        |.|.:
  Fly   274 GLFHRAILMSGSAYSSWALVEDP-VLFAIKLAKEVNCTIPDDINRHHEQIVD--------CLRDV 329

  Fly   292 AAIDQDVINLDEVRSFLLFAFGPVIEPYETDHCVVPKRHKDLLSEAWGNDIPVIV---------- 346
            ..  :|:...|......|.:|||.:     |..|:...|.:|       ||..::
  Fly   330 PL--EDLYLADIQAPNFLTSFGPSV-----DGVVIRPGHSNL-------DIDDLMARNSRRSSAD 380

  Fly   347 ------------------------GGNSFEG-------------------LFSYQLVRKDPWALK 368
                                    .|:||.|                   ||.. :..:..|..
  Fly   381 SGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGV-VTGESIWRF- 443

  Fly   369 NFHNILPREVRETSSLEGQ--DLLVRRLKQLYFNNEMQESMEMFEALNIFSHRQIWHDTHRF--- 428
            :.|:|       .:..||:  |.::|...:..:|..:.|.  .:..:|.::.   |..|.:.
  Fly   444 SAHDI-------QNGFEGERRDKIIRTYVRNAYNYHLNEI--FYTIVNEYTD---WDRTSQHPIN 496

  Fly   429 -----------------------ILARQSYAPKTPT-------------------------YLYR 445
                                   |||..|..|.:.:                         |.|.
  Fly   497 TRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYV 561

  Fly   446 FDFDSPHFNQFRRLVCGDRIRGVAHADELSYLF-------YNIIASKLDKSSMEYKTIERMVGMW 503
            ||:.:...:..:|:       |..|.::|.|:|       ::.......||  |....|.::..|
  Fly   562 FDYQTKDGDYPQRM-------GTVHGEDLPYIFGAPLVDGFSHFPQNYTKS--ETALSEAVMIFW 617

  Fly   504 TSFASSGNPN 513
            |:||.:||||
  Fly   618 TNFARTGNPN 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	160/639 (25%)
		Aes	<117..>221	CDD:223730	47/108 (44%)
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	161/649 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810