Protein Alignment alpha-Est2 and Nlg1

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Alignment Length: 581
• Identity: 149/581 - (25%)
• Similarity: 246/581 - (42%)
• Gaps: 141/581 - (24%)

  Fly    31 HTVILDTKYGQVRGLQRK--TVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVL------ 87
            :|..:..|.|::.|:.|:  ..........|.|:|||:.|.|:.||..|..|.||||:.
  Fly   154 YTQEIQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLP 218

  Fly    88 ----------------NCTTNRSKPMQRNMLLGIVEGSEDCLHLNVYV---KALKSEKPLPVIVW 133
                            |.:..|.|.:.| :|..:...|||||:||:||   :...:.|...|:|:
  Fly   219 PVCPQKLPDLSPHGSENMSRARHKHLSR-LLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVLVY 282

  Fly   134 IYGGGFQKGEASRDIYSPDYFMK-KPVVFVAINYRLAALGFLSLKDPKLDVP--GNAGLKDQVMA 195
            ::|..|:..  |.:.|....... ..|:.|.:||||..||||.   |.:|..  .|..|.||:.|
  Fly   283 LHGESFEWN--SGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLR---PSIDAHNIANYALLDQIAA 342

  Fly   196 LRWISQNIAHFNGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESPDNNW 260
            |.||.:||..|.||.:.:||||.|.|:|.|:.:|.:....||||:||:.||.|:|:|..|   |.
  Fly   343 LHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWAAS---NQ 404

  Fly   261 AFRLAQNLGY--------KGDEKDADVLSFLSKVCARQIAAIDQDVINLDEVRSFLLFAFGPVIE 317
            :.:|...:.:        ..:.:|.|||    ..|.|....  ||::::....:....:.||:::
  Fly   405 SLQLTMQIAHALECPLNEHVEAEDDDVL----LDCLRHRRY--QDILHIPTALTQFSTSLGPIVD 463

  Fly   318 PYETDHCVVPKRHKDLLSEAWGNDIPVIVGGNSFEGLFSYQLVRKDPWAL---KNFHNILPREVR 379
            .:     |:|.:             |..|.|:..|....|.|:    :.:   :::|.:....:.
  Fly   464 GH-----VIPNQ-------------PYKVMGHYTEHFSRYDLL----FGITESESYHTLAALALE 506

  Fly   380 ETSSLEGQDLLVRRLKQLYFN--------NEMQESMEMF----EALNIFSHRQIWHDTHRFILA- 431
            |......:|.|:|...|..|:        ..:::..:|:    :|.|: .||.:..|    ||:
  Fly   507 EGLRENERDNLLRFYMQSRFDIRPDLALAATLKKYQDMYNNPIKATNL-EHRDVVLD----ILSD 566

  Fly   432 RQSYAPKTPT-----------YLYRFDFDS--------PHFNQFRRLVCGDRIRGVAHADELSYL 477
            .:...|...|           |:|.|..:|        ||           .|.|    :||:::
  Fly   567 ARVVGPLLQTGMFHADVNRRNYMYVFGHNSATGPFAHLPH-----------SIMG----EELAFI 616

  Fly   478 FYNIIASKLDKSSMEYKTIERM-----VGMWTSFASSGNPNCPELGSAKWEAVQLKENAVE 533
            |...:|:.....|..|...|::     :..||:|..:|||..|      |:.:.:..:|:|
  Fly   617 FGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAP------WKGIFINSHALE 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	148/578 (26%)
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	148/578 (26%)