Protein Alignment alpha-Est2 and Ces1b

DIOPT Version :9

• Sequence 1: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001074841.1
• Gene: Ces1b / 382044
• MGIID: 3779470
• Length: 567
• Species: Mus musculus
• Alignment Length: 599
• Identity: 166/599 - (27%)
• Similarity: 257/599 - (42%)
• Gaps: 134/599 - (22%)

  Fly    30 GH---TVILDTKYGQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTT 91
            ||   :.::||..|::.|........:.|...|.|:|:||||:|.|||..|:|.|||..|.|.|:
Mouse    18 GHSPSSPVVDTTQGKILGKYTSLEGFEHPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKNATS 82

  Fly    92 NRSKPMQRNMLLGIVEG-------------SEDCLHLNVYVKA-LKSEKPLPVIVWIYGGGFQKG 142
            ......|..:.:.::..             |||||:||:|..| |.....|||:|||:|||...|
Mouse    83 YPPMCSQDAVAVQLLSDMLSTKKESIPPLFSEDCLYLNIYSPADLTKSSLLPVMVWIHGGGLMTG 147

  Fly   143 EASRDIYSP-DYFMKKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHF 206
            .||  :|:. .....:.||.|.|.|||...|..|..|.  ...||....||:.||||:..|||:|
Mouse   148 GAS--LYNGLALSAHENVVVVTIQYRLGIWGLFSTGDE--HSRGNWAHLDQLAALRWVQDNIANF 208

  Fly   207 NGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQS--------------GCALSEW---VE 254
            .|:|:::|:.|.|||..||.|::.:...:.|||:||.:|              .|.||:.   |.
Mouse   209 GGNPDSVTVFGSSAGGVSVSVLVLSPLAKNLFHRAISESSVVLENIVITLDLVACDLSQMIATVS 273

  Fly   255 SPDNNWAFRLAQNLGYKGDEKDADVLSFLSKVCARQIAAIDQDVINLDEVRSFLLFAFGPVIEPY 319
            ..::..:..:.|.|..|.:.:..::...|........|:..:|..::..|
Mouse   274 GCNDTSSTAMVQCLRQKTENELLEITVKLEVTKVGGAASAKKDNTSMSTV--------------- 323

  Fly   320 ETDHCVVPKRHKDLLSEAWGNDIPVIVGGNSFEGLFSYQLVRKDPWALKNFHNILPREVRETSSL 384
             .|..|:||..:::|:|...:.:|.|||.|..|                 |..|:|..:.:..|
Mouse   324 -IDGVVLPKAPEEILAEKSFSTVPYIVGFNKQE-----------------FGWIIPTMLGDLLS- 369

  Fly   385 EGQ------DLLVRRLKQLYFNNEMQESMEMFEA-------------------LNIFSHRQIWHD 424
            ||:      .||:||     |::::..|..:..|                   |::||  .::..
Mouse   370 EGKMNEETASLLLRR-----FHSDLNISESLIPAVIEKYLRGTDDPAKKRDLLLDMFS--DVFFG 427

  Fly   425 THRFILARQSYAPKTPTYLYRFDFDSPHFNQFRR--LVCGDRIRGVAHADELSYLFYNIIASKLD 487
            ....:|:|........||:|.|.: .|.|...:|  .|.||      |.||: :..:.|...|..
Mouse   428 IPAVLLSRSLRDAGVSTYMYEFRY-RPSFVSDKRPQTVEGD------HGDEI-FSVFGIPLLKEG 484

  Fly   488 KSSMEYKTIERMVGMWTSFASSGNPN------CPE---------LGSAKWEAVQLKENAVEKCFN 537
            .|..|....:.::..|.:||.:||||      .||         :|:...:|.:||  |.|..|
Mouse   485 TSEEETNLSKMVMKFWANFARNGNPNGEGLPHWPEYDEKEGYLQIGATTQQAQRLK--AEEVAF- 546

  Fly   538 ISHDLEMRDLPESD 551
             ..:|..::.||:|
Mouse   547 -WTELLAKNPPETD 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	154/564 (27%)
		Aes	<117..>221	CDD:223730	43/105 (41%)
Ces1b	NP_001074841.1	COesterase	19..547	CDD:278561	161/584 (28%)
		Aes	<121..>239	CDD:223730	48/121 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832602
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.650