Protein Alignment alpha-Est2 and Gli

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Alignment Length: 676
• Identity: 180/676 - (26%)
• Similarity: 270/676 - (39%)
• Gaps: 204/676 - (30%)

  Fly     3 VQVGWPKLIKMGAQLVGHKVQQYRLSTGHTVILDTKYGQVRGLQRKTVYDK-------EPYFA-- 58
            |..||.:      .|.| |.::..|:....|.:.|.||||:|. :..:||.       .||.:
  Fly   112 VLAGWRE------DLQG-KQRRDSLTLERDVFVTTNYGQVQGF-KVYMYDNPDPKSFYRPYHSTV 168

  Fly    59 ---------FEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCT------------TNRSKPMQRNML 102
                     |.|||||.||..:.||:.|:....|| :|...            |..:|
  Fly   169 DRVMGECSVFLGIPYALPPTFEGRFKPPRVHRGWQ-LLQAVDFGPACPQPVRYTGATK------- 225

  Fly   103 LGIVEGSEDCLHLNVY---VKALKSEKPLPVIVWIYGGGFQKGEAS---RDIYSPDYFMKKPVVF 161
             ||::..||||:||||   ..|..::| .||:|:|:||.|.:|.::   ..|.:..|    .||.
  Fly   226 -GIMDMDEDCLYLNVYSPKTGAGVAQK-YPVMVYIHGGEFIRGASNLFQGHILASFY----DVVV 284

  Fly   162 VAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSASVH 226
            |.:||||.||||||..|.  :.|||.|:.||.|||||:..||..||||.|:|||.|..||.||..
  Fly   285 VTLNYRLGALGFLSTGDE--NSPGNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGAGGASAG 347

  Fly   227 VMMTTEQTRGLFHKAIMQSGCALSEWVESPDNNWAFRLAQNLGYKGDEKDADVLSFLSKVCARQI 291
            ::|...|||.:..:.|.|||.||::|....|.   :| |||               .|:|..:.:
  Fly   348 LLMVAPQTRNIVRRVIAQSGSALADWALIQDK---YR-AQN---------------TSRVLGQLL 393

  Fly   292 -AAIDQD--VIN-LDEVRSFL------------LFAFGPVIEPYET---DHCVVPKRHKD----- 332
             .:|:..  ::| |...|||.            .|.:|||::...|   |......|.||
  Fly   394 GCSIESSWKLVNCLRTGRSFYELGNAEFSPQVGSFPWGPVLDHNFTLPGDDWYEGWREKDWRFLT 458

  Fly   333 ------LLSEAWGNDIPVIVGGNS------------------FEGLFSYQLVRKDPW-------- 365
                  :.:..:..:|..:.|..:                  .:|.|..|.:|:..:
  Fly   459 QTPETLIRAGKFNRNIQYMTGVTTQEAAFFVAQNESLSPYYELDGRFFDQKIREHVFRYNYTLNP 523

  Fly   366 -----ALKNFHNILPREVRETSSLEGQDLLVRRLKQLYFNNEMQESMEMF--------------- 410
                 |:|..:...|.....|..   :|..:..|..||:...:.:.:::.
  Fly   524 NGVYEAIKYIYTFWPDPNNNTII---RDQYINMLSDLYYRAPVDQMVKLMLEQKVPVYMYVLNTT 585

  Fly   411 -EALNIFSHRQIWHDTHRFILARQSYAPKTPTYLYRFDFDSPHFNQFRRLVCGDRIRGVAHADEL 474
             ||||:...|:..||..|:.|   :.||...|..:      |.....:|.:..|..|.::|
  Fly   586 VEALNLPQWRKYPHDIERYFL---TGAPFMDTEFF------PKKEHLQRNMWTDNDRNMSH---- 637

  Fly   475 SYLFYNIIASKLDKSSMEYKTIERMVGMWTSFASSGNPNCPE--LGSAKWEAVQ--LKENAVEKC 535
               |:                    :..:|:||..|||. |:  ||.....|.|  ::...:...
  Fly   638 ---FF--------------------MQTYTNFARYGNPT-PQQVLGMHFQRAYQGEIRYLNINTT 678

  Fly   536 FNISHDLEMRDLPESDCLAVWDTFYP 561
            :|.|..|..|   :::| |.|..:.|
  Fly   679 YNSSILLNYR---QTEC-AFWTQYLP 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	170/638 (27%)
Gli	NP_476602.1	COesterase	137..695	CDD:395084	170/637 (27%)
		PRK13335	818..>918	CDD:139494