Protein Alignment alpha-Est2 and CG3841

DIOPT Version :9

• Sequence 1: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001188759.1
• Gene: CG3841 / 34278
• FlyBaseID: FBgn0032131
• Length: 564
• Species: Drosophila melanogaster
• Alignment Length: 601
• Identity: 169/601 - (28%)
• Similarity: 250/601 - (41%)
• Gaps: 162/601 - (26%)

  Fly    30 GHTVILDTKYGQVRG-----LQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPW-QGVLN 88
            |...:::...|:::|     ...||:|      ||.||.||:.|||.|||..|.|...| ..|.|
  Fly    26 GDDPVVELSLGRIQGDTMQSFGNKTIY------AFRGIRYAQSPVGQLRFANPVPETSWGDEVFN 84

  Fly    89 CTTNR---SKPMQRNMLLGIVE-GSEDCLHLNVYVKALKSEKPLPVIVWIYGGG--FQKGEASRD 147
            .|::.   .:|       |:|. .|||||.:||:.|:.  |...||:|:|:||.  ...|.:|.:
  Fly    85 ATSDSLVCPQP-------GVVSLMSEDCLKINVFTKSF--EDKFPVMVYIHGGANVLGSGHSSYE 140

  Fly   148 IYSPDYFMKKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNN 212
            . .|.|.:.:.|||||.||||.||||||....  :..||.|..||||||.|:..:|:||.|||..
  Fly   141 A-GPQYLLDQDVVFVAFNYRLGALGFLSTNSS--ETKGNFGFLDQVMALEWVRDHISHFGGDPEL 202

  Fly   213 ITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESPDN-NWAFRLAQNLG---YKGD 273
            :|::|.||||.:|.:.:.:..:.||||:||:.||.|.:.:  ..|| .|..:||:.||   |
  Fly   203 VTIIGISAGSMAVSLHLASPLSAGLFHRAILMSGSATNHF--DIDNLFWTRKLARELGCPMY--- 262

  Fly   274 EKDADVLSFLSKVCARQIAAI-----DQDVINLDEVRSFLLFAFGPVIEPYETDHCVVPKRHKDL 333
             ...||:..|......:|..:     ...::|:.              ..||.|...:.....:|
  Fly   263 -DPTDVVECLRNETWTRIVEVCKAWETYQLVNMK--------------WNYEIDGHFLHNHPTEL 312

  Fly   334 LSEAWGNDIPVIVGGNSFEGLFSYQLVRKDPWALKNFHNILPREVRETSSLEGQDLL-------- 390
            :.|...|.:|:::...:.|  |.|.         .|.|            ||.|.||
  Fly   313 IKEGNFNKVPLLISFTANE--FDYN---------ANVH------------LENQHLLHDFASNFV 354

  Fly   391 ---------------VRRLKQLYFNNEM----QESMEMFEALNIFSHRQIWHDTHRFILARQSYA 436
                           ..:||..|..:..    .|::|.|.  .|||...|.|..||.:.....:
  Fly   355 DYAPELFLYRHDAQIGEKLKDFYLGDNTTEINSENIENFG--QIFSDAYIGHGVHRLVQLASHF- 416

  Fly   437 PKTPTYLYRFDFDSPHFNQFRRLVCGDRIR-----------GVAHADELSYL----FYNIIASKL 486
              ||.|..|.|:            .||:..           ||.|||:|.|:    :|..:.:..
  Fly   417 --TPVYYTRMDY------------VGDQSLSAPLNGENKPVGVGHADDLHYVLPGYWYGPLMAAN 467

  Fly   487 DKSSMEYKTIERMVGMWTSFASSGNP-NCPELGSAKW-----EAVQLKENAVEKCFNISHDLEMR 545
            |.   :...:||:...:|.||.:|.| |..::    |     ..:::..|.|.        .::.
  Fly   468 DS---DVFMMERLTSWFTHFAKTGTPLNSTDI----WPPCNSTVLKMLYNGVV--------TQVG 517

  Fly   546 DLPESDCLAVWDTFYP 561
            ....|:..||||..:|
  Fly   518 SPGYSNRYAVWDKLFP 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	160/559 (29%)
		Aes	<117..>221	CDD:223730	47/105 (45%)
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	164/593 (28%)
		Aes	<116..>235	CDD:223730	55/121 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467399
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I1664
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43142
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
	9	8.890