Protein Alignment alpha-Est2 and Nlg3

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: XP_061500330.1
• Gene: Nlg3 / 3290865
• VectorBaseID: AGAMI1_000316
• Length: 952
• Species: Anopheles gambiae
• Alignment Length: 626
• Identity: 162/626 - (25%)
• Similarity: 250/626 - (39%)
• Gaps: 133/626 - (21%)

  Fly    34 ILDTKYGQVRG-LQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTTNRSKPM 97
            |:.||||.|.| ::.......:|..||.|:|||.||||:|||..|.....|.||..  .:|..|:
Mosquito    65 IVHTKYGAVSGTIEHLDGRHLDPVEAFRGVPYASPPVGNLRFMPPVTGALWSGVKK--ADRFSPV 127

  Fly    98 -------------------------QRNMLLGIVEGSEDCLHLNVYV------KALKSEKPLPVI 131
                                     .|.:|..:...|||||:||:||      :...|.....|:
Mosquito   128 CPQRLPDIYNETAALERMPRGRLEYLRRLLPYLRNQSEDCLYLNIYVPTQAGSRESSSTSKYAVV 192

  Fly   132 VWIYGGGFQ--KGEASRDIYSPDYFMKKPVVFVAINYRLAALGFLSLK-DPKLDVPGNAGLKDQV 193
            |:::|..::  .|..........|   ..::.|.|||||..||||:.. |.....|.|.||.|.:
Mosquito   193 VFVHGESYEWNSGNPYDGSVLASY---GQILVVTINYRLGILGFLNANVDRFSKAPANYGLMDII 254

  Fly   194 MALRWISQNIAHFNGDPNNITLMGESAGSASVHVMMTTEQT-RG-LFHKAIMQSGCALSEW--VE 254
            .||.||.:||..|.|||.::||.|...|:|.||.::.:... .| |||:|||.||..|:.|  |.
Mosquito   255 AALHWIQENIEAFGGDPKSVTLAGHGTGAACVHFLIASAAVPEGLLFHRAIMMSGSGLAPWSLVG 319

  Fly   255 SPDN---------NWAFRLAQNLGYK--GDEKDADVLSFLSKVCARQIA-----AIDQDVINLDE 303
            .|..         |.:..|...|..|  .|:...|:||  :.|.|....     ::|..||:..|
Mosquito   320 EPAKFAAYVSHHVNCSPDLPHQLLLKCLRDKPLEDILS--TSVRAPDFGNAFGPSVDGVVIDTGE 382

  Fly   304 VRS-----FLLFAFGP-VIEPYETDHCVVPKRHKDLLSEAWGNDI---PVIVGGNSFEGLFSYQL 359
            ::.     :..::..| ..:|....|..:...:..||.:...|.:   .::||....|..|::..
Mosquito   383 IQQMDGTHYSDYSGNPAATKPSAHIHNTLNTINAILLRKLAINKLSKYDLLVGVTRAEAYFAFNS 447

  Fly   360 ------VRKDPWA--LKNFHNILPREVRETSSLEGQDLLVRRLKQLYFN---------NEMQESM 407
                  :..|..|  |||:       ||.|.|....::|...:.: |.:         |...|::
Mosquito   448 EDVQYGIEADRRAKILKNY-------VRSTYSFHLNEILATIVNE-YTDWERPVQHPINIRDETL 504

  Fly   408 EMFEALNIFSHRQIWHDTHRFILARQSYAPKTPTYLYRFDFDSPHFNQFRRLVCGDRIRGVAHAD 472
            |......|.:......|.|.        |....::||.||:.: .|..|      .:.:|..|.:
Mosquito   505 EALSDARIVAPAVQTADLHS--------ADHRNSFLYVFDYQT-KFGDF------PQRQGCIHGE 554

  Fly   473 ELSYLF-------YNIIASKLDKSSMEYKTIERMVGMWTSFASSGNPN----------CPELGSA 520
            :|.|||       :|.......||  |....|.::..|::|..:||||          .....:.
Mosquito   555 DLPYLFGAPLVGGFNHFTRNYTKS--EIALSEAVMIYWSNFIRTGNPNEQLENDHVRDRTRFKNI 617

  Fly   521 KWEAVQLKENAVEKCFNISHDLEMRDLPESDCLAVWDTFYP 561
            :|...   |:..:|..|:....::::...:..|:.|....|
Mosquito   618 EWTPY---ESVHKKYLNLDTKPKLKNHYRAHRLSFWLNLVP 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	160/619 (26%)
Nlg3	XP_061500330.1	None