Protein Alignment alpha-Est2 and Nceh1

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001120996.1
• Gene: Nceh1 / 294930
• RGDID: 1311104
• Length: 408
• Species: Rattus norvegicus
• Alignment Length: 203
• Identity: 43/203 - (21%)
• Similarity: 74/203 - (36%)
• Gaps: 63/203 - (31%)

  Fly    56 YFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTTNRSKPMQRNML--LG-------------- 104
            |:.:..:|.|   |.|          ||:.:|...|.|......|::  ||
  Rat    17 YYVYIPLPSA---VSD----------PWKLMLLDATFRGAQQVSNLIHSLGLSHHLITLNFIIIS 68

  Fly   105 -------------IVEGSEDCLHLNVYVKALKSEKPL-PVIVWIYGGGFQKGEASRDIYSPDYFM 155
                         :.:...|.:.:.|:....|.::|| ..:|:|:|||:....|....|  |...
  Rat    69 FGKKSARSSPRVKVTDTDFDGVEVRVFEGPPKPDEPLRRSVVYIHGGGWALASAKISYY--DQLC 131

  Fly   156 -----KKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQN--IAHFNGDPNNI 213
                 :...|.|:|.|||.         |::..|..  :.|.:.|.::..|.  :..:..||..:
  Rat   132 TAMAEELNAVIVSIEYRLV---------PQVYFPEQ--IHDVIRATKYFLQPEVLDKYKVDPGRV 185

  Fly   214 TLMGESAG 221
            .:.|:|||
  Rat   186 GVSGDSAG 193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	43/203 (21%)
Nceh1	NP_001120996.1	Abhydrolase_3	109..381	CDD:400284	25/98 (26%)
		Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3	113..115		0/1 (0%)