Protein Alignment alpha-Est2 and Ces4a

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001099646.1
• Gene: Ces4a / 291955
• RGDID: 1307418
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 597
• Identity: 173/597 - (28%)
• Similarity: 264/597 - (44%)
• Gaps: 105/597 - (17%)

  Fly     4 QVGWPKLIKMGAQLVGHKVQQYRLSTGHT--VILDTKYGQVRGLQRKTVY-DKEPYFAFEGIPYA 65
            :.||.....:...|....|.|..|...||  .:|.||:|.::|   |.|: ...|...|.|:|::
  Rat     3 EAGWSMKWTLDLSLTLWLVVQTALGALHTKEPLLITKHGILQG---KQVHVGDTPIRVFLGVPFS 64

  Fly    66 KPPVGDLRFRAPQPPEPWQGVLNCTTNRSKPMQR------NMLLGI------VEGSEDCLHLNVY 118
            :||||..||..|:||.||.|:.:.||.....:|.      :|.|..      :..|||||:||||
  Rat    65 QPPVGTRRFAPPEPPLPWNGIRDATTYPPSCLQESWGQITSMYLNTRKQYEWLHFSEDCLYLNVY 129

  Fly   119 VKALKSEKP-LPVIVWIYGGGFQKGEASRDIYSPDYFMKKPVVFVAINYRLAALGFLSLKDPKLD 182
            ...|....| |||:||..||.|..|.|| .....:...:..||.|.:.|||..|||.|..:.  .
  Rat   130 APVLAPGDPLLPVMVWFPGGAFLVGSAS-TYEGSELAARGKVVLVFLQYRLGILGFFSTGNS--H 191

  Fly   183 VPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGC 247
            ..||.||.||:.||||:.:||..|.|||:::||.|:|||:.||..::.:...:||||:||.|||.
  Rat   192 ARGNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGLLMSPLAQGLFHQAISQSGT 256

  Fly   248 A-LSEWVESPDNNWAFRLAQNLGYKGDEKDADVLSFLSKVCARQIAAIDQDVINLDEVRSF---- 307
            | |..::.......|.::|...|.     |.:....:.| |.:.:.|  :.|:.:.:..:|
  Rat   257 AVLKTFITHDPLKSAKKIAHLAGC-----DHNSTKIMVK-CLKALPA--EKVMLVSKKMTFFRAN 313

  Fly   308 -------LLFAFGPVIEPYETDHCVVPKRHKDLLSEAWGNDIPVIVGGNSFEGLFSYQL------ 359
                   :::...||:     |..|.|:....||:......:|.::|.||.|  |.:.|
  Rat   314 SHKDPKDIVWFLSPVV-----DGLVFPEDPVVLLTRGQVKPVPYLLGVNSAE--FEWSLPFLMKL 371

  Fly   360 -----------VRKDPWALKNFHNI----LPREVRE--TSSLEGQDLLVRRLKQLYFNNEMQESM 407
                       :.|..|:.....||    :|...||  :.::...|..:       |.|.:.:.:
  Rat   372 QLNQRIMNKNYITKLLWSCSILLNITEEQIPLVAREYLSDAISHHDWKM-------FRNHLIDLV 429

  Fly   408 EMFEALNIFSHRQIWHDTHRFILARQSYAPKTPTYLYRFDFDSPHFNQFRRLVCGDRIRGVAHAD 472
            .  :|..:::..|         .||......:|.|||.|...:|      .::...|..|..|.|
  Rat   430 G--DATFVYATLQ---------AARYHRDAGSPVYLYEFKHHAP------GIIVKPRSDGADHGD 477

  Fly   473 ELSYLFYNIIASKLDKSSMEYKTIE---RMVGMWTSFASSGNPNCPELGSAKWEAVQLKENAVEK 534
            ||||||    .|...|.|...:..|   :|:..|.:||.:|:||..||  ..|.....:|..::.
  Rat   478 ELSYLF----GSPFSKGSSRGEEKEFSLQMMKYWANFAHTGDPNDREL--PYWPRFDKEEKYLQL 536

  Fly   535 CFNISHDLEMRD 546
            .|:....:::|:
  Rat   537 DFDTRVGVKLRE 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	165/565 (29%)
Ces4a	NP_001099646.1	COesterase	33..554	CDD:395084	165/567 (29%)