Protein Alignment alpha-Est2 and cest-9.2

DIOPT Version :9

• Sequence 1: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_741910.3
• Gene: cest-9.2 / 259729
• WormBaseID: WBGene00007695
• Length: 617
• Species: Caenorhabditis elegans
• Alignment Length: 544
• Identity: 129/544 - (23%)
• Similarity: 223/544 - (40%)
• Gaps: 130/544 - (23%)

  Fly    34 ILDTKYGQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLN-------CTT 91
            :::|.||:|||:...: .|....:.|:.:|:||||:|.|||..||.|:.|.|||:       |.:
 Worm    23 VIETSYGRVRGITEWS-DDNNHKYMFKSVPFAKPPIGKLRFAPPQYPDSWSGVLDASKYSPACLS 86

  Fly    92 N---RSKPMQRNMLLGIVEGSEDCLHLNVYV--KALKSEKPLPVIVWIYGGGFQKGEASR--DIY 149
            |   .|.|.:        ..|||||::|::.  |.|:|:  ..|||:.:||.:....|:.  |.:
 Worm    87 NSSTTSTPQE--------HVSEDCLYINIFTSEKCLRSK--CAVIVYFHGGAYNGDSATMFPDNF 141

  Fly   150 SPDYFMKKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNIT 214
            ..:.::.:.|:......||...|.|.. .|...:..|..:.|.|.||.::...|.:|.|||..:|
 Worm   142 ILERYVAEDVILAIPGVRLGVFGQLYF-GPSALLTENLFMFDAVQALDFVHNEIPNFGGDPKQVT 205

  Fly   215 LMGESAGSASVHVM---MTTEQTRGLFHKAIMQSGCALSEWVESPDNNWAFRLAQNLG-YKGDEK 275
            :||.|:|...|..:   .:.:....||.:.|:.||..:..:.:...:| :|.:::.|| :.|.::
 Worm   206 IMGHSSGGTLVEALGFSNSVDPDLKLFQQIIVLSGTGMFGFYDLLVDN-SFIISEKLGCFNGTQE 269

  Fly   276 ---DADVLSFLSKVCARQIAAID--------QDVINL---DEVRSFLLFAFGPVIEPYETDHCVV 326
               ||::...|.  |.|||...:        :||..|   ..:|..........||.:.  :...
 Worm   270 ERTDANIAEILE--CMRQIDGHEIVGMQKHMEDVYKLTFKSLLRGAPFMELNGKIEKFR--NSTS 330

  Fly   327 PKRHKDLLSEAWGNDIPVIVGGNSFEGLFSYQLVRKDPWALKNFHNILPREVRETSS---LEGQD 388
            |:                    |:..|...|:           |.|.:.|.:..|::   .|...
 Worm   331 PR--------------------NAIFGTTEYE-----------FRNEVERYLYITTTFLDFENPV 364

  Fly   389 LLVRRLKQLYFNNEMQESMEMF---EALNIFSHRQIWHDTHRFILARQS---YAPKTPTYLYRFD 447
            .:.:     :|::|:.::|:..   :|::||.....:...    :|...   |..:|..:.|.|.
 Worm   365 AVAQ-----HFDDELMQNMDTMINGDAVSIFVSAAAFSSA----MANAGADVYLFETRQWPYSFH 420

  Fly   448 F-DSPHFNQFRRLVCGDRIRGVAHADELSYL--FYNIIASKLDKSSMEYKTIERMVGMWTSFASS 509
            . |..:|....        |.|.|..::..|  ||    |||                ..:|..:
 Worm   421 VSDMQYFIGIH--------REVLHTHDMDILDSFY----SKL----------------LVNFTKT 457

  Fly   510 GNPNCPELGSAKWEAVQLKENAVE 533
            |.|: ||..|.:.|.:...|..|:
 Worm   458 GAPS-PEWNSLEPEKMNYLELRVD 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	126/532 (24%)
		Aes	<117..>221	CDD:223730	30/107 (28%)
cest-9.2	NP_741910.3	Abhydrolase	19..501	CDD:304388	129/544 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157177
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740