Protein Alignment alpha-Est2 and Ces1a

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001013786.2
• Gene: Ces1a / 244595
• MGIID: 3648919
• Length: 563
• Species: Mus musculus
• Alignment Length: 574
• Identity: 173/574 - (30%)
• Similarity: 252/574 - (43%)
• Gaps: 114/574 - (19%)

  Fly    27 LSTGH---TVILDTKYGQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLN 88
            ::.||   ..::||..|:|.|.........:|...|.|:|:||||:|.|||..|||.|.|..|.|
Mouse    15 MALGHLSSPPVVDTLQGKVMGKYISLEGSAQPVAVFLGVPFAKPPLGPLRFAPPQPAETWSSVKN 79

  Fly    89 CTTNRSKPMQRNMLLGI----------------VEGSEDCLHLNVYVKA-LKSEKPLPVIVWIYG 136
            .|   |.|...:.:.|:                :|.|||||:||:|... |.|:..|||:||::|
Mouse    80 TT---SYPPMCSQITGVGPVLSDVFTNQLENVPLEYSEDCLYLNIYSPTDLTSKDRLPVMVWVHG 141

  Fly   137 GGFQKGEASRDIYSPDYF------MKKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMA 195
            ||...|.||.       |      ..:.||.|.|.|||...||||..|.  ...||.|..|||.|
Mouse   142 GGLLSGGAST-------FDGLALSTHENVVIVVIQYRLGIWGFLSTGDE--HSRGNWGHLDQVAA 197

  Fly   196 LRWISQNIAHFNGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESPDNNW 260
            |:|:..|||:|.|||:::||.|||||..||.|::.:..|:.||.:||.:||.||:..:......
Mouse   198 LQWVQNNIANFGGDPSSVTLFGESAGGESVSVLVLSPLTKNLFQRAISESGVALTPCLFRETTR- 261

  Fly   261 AFRLAQNLGYKGD---EKDADVLSFLSKVCARQIAAIDQDVINLDEVRSFLLFAFGPVIEPYE-- 320
              |.|:.:.....   ...||::..|.:....::.|...      :::.|.|...|...|.|.
Mouse   262 --RAAEQVAIATGCVATTSADIVHCLREKTEEELLATTL------KMKFFALDLLGDPRESYPFL 318

  Fly   321 ---TDHCVVPKRHKDLLSEAWGNDIPVIVGGNSFE-GLF-----SY-----QLVRKDP----WAL 367
               .|..|:||..:::|:|...|.:|.|||.|..| |.|     .|     :|.:|..    |..
Mouse   319 TTVIDGVVLPKAPEEILAEKSFNTVPYIVGINKQEFGWFIPMMMGYPLSEGKLDQKSATSLLWKS 383

  Fly   368 KNFHNILPREVRETSS---LEGQDLLVRRLKQLYFNNEMQESMEMFEALNIFSHRQIWHDTHRFI 429
            ....|| .:|:...::   |.|.|...:: |.|:.  :|...: :|...::             |
Mouse   384 YPLTNI-SKELTPVATEKYLGGSDCPDKK-KDLFL--DMMGDV-LFAVPSV-------------I 430

  Fly   430 LARQSYAPKTPTYLYRFDFDSPHFNQFR-RLVCGDRIRGVAHADELSYLFYNIIASKLDKSSMEY 493
            :||.......|||:|.|.:.....:..| :.|..|      |.||: |..:.....|...|..|.
Mouse   431 VARYHRDAGAPTYMYEFKYHPSFVSDMRPKTVIAD------HGDEV-YSVWGTPFLKEGASEEEI 488

  Fly   494 KTIERMVGMWTSFASSGNPN------CPE---------LGSAKWEAVQLKENAV 532
            .....|:..|.:||.:||||      .||         :|:...:|.:||:..|
Mouse   489 NLSTMMMKFWGNFARNGNPNGEGLPHWPEYGEKESYLQIGATTQQAQRLKDKEV 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	171/564 (30%)
Ces1a	NP_001013786.2	COesterase	22..545	CDD:395084	171/567 (30%)