Protein Alignment alpha-Est2 and Ces2e

DIOPT Version :9

• Sequence 1: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001157228.1
• Gene: Ces2e / 234673
• MGIID: 2443170
• Length: 559
• Species: Mus musculus
• Alignment Length: 576
• Identity: 180/576 - (31%)
• Similarity: 254/576 - (44%)
• Gaps: 110/576 - (19%)

  Fly     5 VGWPKLIKMGAQLVGHKVQQYRLSTGHTVILDTKYGQVRGLQRKTVYDKEPYFA---FEGIPYAK 66
            :||...:..|..|:...||.   ....:.|.:|..|||||   ..|:.|:...|   |.|||:||
Mouse     7 LGWLNAVACGVLLLVLHVQG---QDSASPIRNTHTGQVRG---SLVHVKDTDIAVHTFLGIPFAK 65

  Fly    67 PPVGDLRFRAPQPPEPWQGVLNCTTNRSKPMQR------------NMLLGIVEGSEDCLHLNVYV 119
            ||||.|||..|:.||||.||.:.|::.:..:|.            |::|..:..|||||:||:||
Mouse    66 PPVGPLRFAPPEAPEPWSGVRDGTSHPNMCLQNDNLMGSEDLKMMNLILPPISMSEDCLYLNIYV 130

  Fly   120 KALKSE-KPLPVIVWIYGGGFQKGEASRDIYSPDYF-MKKPVVFVAINYRLAALGFLSLKDPKLD 182
            .|...| ..|||:|||:||....|.||  :|..... ..:.||.|||.|||..|||.|..|.  .
Mouse   131 PAHAHEGSNLPVMVWIHGGALTVGMAS--MYDGSMLAATEDVVVVAIQYRLGVLGFFSTGDQ--H 191

  Fly   183 VPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGC 247
            ..||.|..|||.||||:.|||.||.|:|:.:|:.|||||..||...:.:..::||||.|||:||.
Mouse   192 AKGNWGYLDQVAALRWVQQNIVHFGGNPDRVTIFGESAGGTSVSSHVVSPMSQGLFHGAIMESGV 256

  Fly   248 ALSEWVESPDNNWAFRLAQNLGYKGDEKDADVLSFLSKVCARQIAAIDQDVINLDEVRSFLLFAF 312
            |:...:.|..:....|:..||     ...|.|.|.....|.|  ...:.:::.:::|...:
Mouse   257 AVLPDLISSSSEMVHRIVANL-----SGCAAVNSETLMCCLR--GKNEAEMLAINKVFKII---- 310

  Fly   313 GPVIEPYETDHCVVPKRHKDLLSEAWGNDIPVIVGGNSFEGLFSY-------------QLVRKD- 363
                 |...|...:||..::|::....:.:|.|:|.|:.|  :.:             ::.||.
Mouse   311 -----PGVVDGEFLPKHPQELMASKDFHPVPSIIGINNDE--YGWILPTIMDPAQKIEEITRKTL 368

  Fly   364 PWALKN--FHNILPREVRETSSLEGQDLLVRRLK---------QLYFNNEMQESMEMFEALNIFS 417
            |..||:  ...:||.|.        .|||:....         |..|.....:.|.:..||.: :
Mouse   369 PAVLKSTALKMMLPPEC--------GDLLMEEYMGDTEDPETLQAQFREMKGDFMFVIPALQV-A 424

  Fly   418 HRQIWHDTHRFILARQSYAPKTPTYLYRFDFDSPHFNQFR-RLVCGDRIRGVAHADEL----SYL 477
            |.|..|               .|.|.|.|......|..|| ..|..|      |.||:    .|.
Mouse   425 HFQRSH---------------APVYFYEFQHRPSFFKDFRPPYVKAD------HGDEIFLVFGYQ 468

  Fly   478 FYNIIASKLDKSSMEYKTIERMVGMWTSFASSGNPNCPELGSAKWEAVQLKENAVE 533
            |.||   ||..:..|.:...|::..|.:||..||||..  |...|..:...|..::
Mouse   469 FGNI---KLPYTEEEEQLSRRIMKYWANFARHGNPNSE--GLPYWPVMDHDEQYLQ 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	172/537 (32%)
		Aes	<117..>221	CDD:223730	50/105 (48%)
Ces2e	NP_001157228.1	COesterase	30..538	CDD:278561	174/550 (32%)
		Aes	<128..>231	CDD:223730	51/106 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832683
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.640