Protein Alignment alpha-Est2 and cest-8

DIOPT Version :9

• Sequence 1: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001359583.1
• Gene: cest-8 / 182818
• WormBaseID: WBGene00007691
• Length: 605
• Species: Caenorhabditis elegans
• Alignment Length: 548
• Identity: 119/548 - (21%)
• Similarity: 209/548 - (38%)
• Gaps: 162/548 - (29%)

  Fly    34 ILDTKYGQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTTNRSKPMQ 98
            |::|.||::||:...: .|....|.|:.:|:||||:|:|||..||..:.|.|:|:.:...:..|.
 Worm    20 IINTSYGKLRGMAEWS-DDANHKFTFKSVPFAKPPIGNLRFAPPQKLDHWDGILDASVYSAACMS 83

  Fly    99 RNMLLGIVEGSEDCLHLNVYV--KALKSEKPLPVIVWIYGGGFQKGEAS--RDIYSPDYFMKKPV 159
            .:.|......:||||::|::.  |.|||:  ..|||:.:||.:....|:  .|.:..|.::.:.|
 Worm    84 NSTLTTQSYVNEDCLYINIFTSEKCLKSK--CSVIVYFHGGAYNTESATMFSDRFILDRYVHEDV 146

  Fly   160 VFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSAS 224
            :||....||...|.|.. .|...:..|..:.|.::||.::...|::|.|||..:|:||.|:|...
 Worm   147 IFVIPAVRLGVFGQLYF-GPNAYLTENLFMFDAILALDFVHNEISNFGGDPEKVTIMGHSSGGTL 210

  Fly   225 VHVM----MTTEQTRGLFHKAIMQSGCALSEWVESPDNNWAFRLAQNLG-YKGDEKD------AD 278
            |..:    |...:.: ||.:.||.|...:..:.:...:| :|.:.:.|| :.|.:::      |:
 Worm   211 VEALGFSSMVDPELK-LFQQMIMLSSTGMFGFDDLVIDN-SFTIVEKLGCFNGTKEERNTVNVAE 273

  Fly   279 VLSFLSKVCARQIAAIDQDVINLDEVRSFLLFAFGPVIEPYETDHCVVPKRHKDLLSEAWGNDIP 343
            .|..:..:...:|..:.|.:..:|::.
 Worm   274 TLDCMRHIDGYEILRVQQKMELMDQLS-------------------------------------- 300

  Fly   344 VIVGGNSFEGLFSYQLVRKDPWALKNFH------NILPREVRETSSLEGQDLLVRRLKQLYFNNE 402
                       |.| |:|..|:.|.|.:      |..||..
 Worm   301 -----------FKY-LLRGAPFMLLNGNIADLKKNTSPRNA------------------------ 329

  Fly   403 MQESMEMFEALNIFSHRQIWHDTHRFILARQSYAPKTPTYLYRFDFDSP----------HFNQFR 457
                        ||...:     |.|....:.|...|.|:|   |:::|          ......
 Worm   330 ------------IFGTTE-----HEFFDVTEKYLYITVTFL---DYENPVAVARNYDGRLMKNME 374

  Fly   458 RLVCGDR----------IRGVAHADELSYLFYNIIASKLDKSSMEY---------KTIERMV--- 500
            .::.||.          ...:|:|....:||....:..:..|.|:|         :||:..:
 Worm   375 TMITGDSAAIFVSTATCAAAMANAGADVFLFETRQSYSVHVSDMQYFIGNHCAHNRTIDIDILDS 439

  Fly   501 ---GMWTSFASSGNPNCPELGSAKWEAV 525
               .:.|:|...|.|      |..|:.|
 Worm   440 FYSKLLTNFTKHGKP------SPGWDPV 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	117/544 (22%)
		Aes	<117..>221	CDD:223730	33/107 (31%)
cest-8	NP_001359583.1	Abhydrolase	19..495	CDD:389770	119/548 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157143
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740