Protein Alignment alpha-Est2 and ace-1

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_510660.1
• Gene: ace-1 / 181706
• WormBaseID: WBGene00000035
• Length: 620
• Species: Caenorhabditis elegans
• Alignment Length: 594
• Identity: 165/594 - (27%)
• Similarity: 258/594 - (43%)
• Gaps: 153/594 - (25%)

  Fly    54 EPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTTNRSKPMQ-RNMLLGIVEG--------- 108
            :|...|:|||:|:||||:|||:.|:|.:||:..||.||..:..:| .:...|...|
 Worm    40 KPLTRFQGIPFAEPPVGNLRFKKPKPKQPWRIPLNATTPPNSCIQSEDTYFGDFYGSTMWNANTK 104

  Fly   109 -SEDCLHLNVYVKA-LKSEKPLPVIVWIYGGGFQKGEASRDIYSPDYF-MKKPVVFVAINYRLAA 170
             |||||:|||||.. :...|.|.|:||:|||||..|.|:.|:|..... :::.|:.||:|||::.
 Worm   105 LSEDCLYLNVYVPGKVDPNKKLAVMVWVYGGGFWSGTATLDVYDGRILTVEENVILVAMNYRVSI 169

  Fly   171 LGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSASVHVMMTTEQTR 235
            .|||.:..|  :.|||.|:.||::|::|:.:||..|.||.:.|||.|||||:|||.:.|.:.::.
 Worm   170 FGFLYMNRP--EAPGNMGMWDQLLAMKWVHKNIDLFGGDLSRITLFGESAGAASVSIHMLSPKSA 232

  Fly   236 GLFHKAIMQSGCALSEWVESPDNNWAFRLAQ-----------NLGYKGDEKDADVLSFLSKVCAR 289
            ..||:||:|||.|.|.|...|.:   ..||:           |:.....:.|. :|....:.
 Worm   233 PYFHRAIIQSGSATSPWAIEPRD---VALARAVILYNAMKCGNMSLINPDYDR-ILDCFQRA--- 290

  Fly   290 QIAAIDQDVINLDE---VRSFLLFAFGPVIEPYETDHCVVPKRHKDLLSE------AWGN--DIP 343
                 |.|.:..:|   ||.|..|.:.||::             .|.|.|      ..||  ...
 Worm   291 -----DADALRENEWAPVREFGDFPWVPVVD-------------GDFLLENAQTSLKQGNFKKTQ 337

  Fly   344 VIVGGNSFEGLF--SYQLVRKDPWA---------------LKNFHNILPREVRETS--------S 383
            ::.|.|..|.::  :|||....|.|               :|...::|||::.:..        .
 Worm   338 LLAGSNRDESIYFLTYQLPDIFPVADFFTKTDFIKDRQLWIKGVKDLLPRQILKCQLTLAAVLHE 402

  Fly   384 LEGQDLLV----------RRLKQLYFN---NEMQESMEMFEALNIFSHRQIWHDTHRFILARQSY 435
            .|.|||.|          :.|...:|.   |||           ..:|.:...||:.:....::.
 Worm   403 YEPQDLPVTPRDWINAMDKMLGDYHFTCSVNEM-----------ALAHTKHGGDTYYYYFTHRAS 456

  Fly   436 APKTPTYLYRFDFDSPHFNQFRRLVCGDRIRGVAHADELSYLFYNIIASK-LDKSSMEYKTIERM 499
            ....|.::                       ||.|..|::::|...:..| .:.:..|.:...|.
 Worm   457 QQTWPEWM-----------------------GVLHGYEINFIFGEPLNQKRFNYTDEERELSNRF 498

  Fly   500 VGMWTSFASSGNPNCPELGS------AKWEAVQLK------ENAVEKCFNISHDLEMRDLPESDC 552
            :..|.:||.:|:||..|.||      .|:.:|.::      |::......|.|.      |....
 Worm   499 MRYWANFAKTGDPNKNEDGSFTQDVWPKYNSVSMEYMNMTVESSYPSMKRIGHG------PRRKE 557

  Fly   553 LAVWDTFYP 561
            .|.|..:.|
 Worm   558 CAFWKAYLP 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	163/587 (28%)
ace-1	NP_510660.1	Esterase_lipase	20..543	CDD:238191	159/563 (28%)