Protein Alignment alpha-Est2 and cest-3

DIOPT Version :9

• Sequence 1: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_510042.2
• Gene: cest-3 / 181385
• WormBaseID: WBGene00008451
• Length: 588
• Species: Caenorhabditis elegans
• Alignment Length: 514
• Identity: 128/514 - (24%)
• Similarity: 218/514 - (42%)
• Gaps: 98/514 - (19%)

  Fly    34 ILDTKYGQVRGLQRKTV-YDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLN-------CT 90
            |:.|.||::.|   ||| .|:.   .|:.:|:||||:|.|||..|:...||:.:.|       |.
 Worm    23 IISTTYGKLEG---KTVNVDQH---MFKNVPFAKPPLGKLRFSLPEWTNPWKNIRNATEYSPSCF 81

  Fly    91 TNRSKPMQRNMLLGIVEGSEDCLHLNVYVK--ALKSEKPLPVIVWIYGGGFQKGEASR--DIYSP 151
            :|.|.....|..    ..|||||:|||:..  .||| |....:|:.:|||.....|.:  |.:..
 Worm    82 SNSSMRTDSNFF----PMSEDCLYLNVFTNEYCLKS-KNCSTVVYYHGGGINMDSAVQFNDTFIL 141

  Fly   152 DYFMKKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLM 216
            :.::|:.|||:...|||...|.|......| ||.|..:.|..:|||:|.|.|::|.|..::|.||
 Worm   142 ERYVKENVVFIIPAYRLGIFGLLYFGSNNL-VPQNLAIHDCELALRFIHQEISNFGGHKDDINLM 205

  Fly   217 GESAGSASVHVMMT------TEQTRGLFHKAIMQSGCALSEWVESPDNNWAFRLAQNLG-YKGD- 273
            |.|||:   |:.:.      .:....|.::.|:.|.....:..|....| .:..|:.:| ||.:
 Worm   206 GHSAGA---HISLIFGFSRHIDPDHKLINRIIVLSPVPSYDMPELLIKN-CYDFAERVGCYKRNV 266

  Fly   274 -EKDADVLSFLSKVCARQIAAIDQDVINLDEVRSFLLFAFGPVIEPYETDHCVVPKRH---KDLL 334
             .:|.:::..|.|..||.:.:: |.::..|.:..:...|..|.:  |..:.....|.:   :|:|
 Worm   267 TARDTEIVKCLRKKDARGLMSM-QRLMENDRLYFWNFLAGEPFM--YRDESIADFKEYAVKRDML 328

  Fly   335 SEAWGNDIPVI-----------VGGNSFEGLFSYQLVRKDPWALKNFHNILPREVRETSSLEGQD 388
            .   ||.:..:           :.|:..:....|::..|    ...:|:..|  |..|.....|.
 Worm   329 I---GNTVDEVKWKRLKKENPAIAGSFMDWENPYEVAHK----FNFYHDSAP--VNSTYESFTQG 384

  Fly   389 LLVRRLK------------QLYFNNEMQES----MEMFEALNIFSHRQIWHDTHRFILARQSYAP 437
            :.|....            .|:.:|:...|    |:.|    :.:||:.:|.:...|:  .::..
 Worm   385 IFVSTATYAEAQANAGGTVYLFQSNQQPSSHVSDMQYF----VGTHREDYHTSDMDIM--DTFYS 443

  Fly   438 KTPTYLYRFDFDSP--------HFNQFRRLVCGD-----RIRGVAHADELSYLFYNIIA 483
            |......:|...||        ..|.:...|..:     |:....|..::::.|.|:.|
 Worm   444 KMIVNFTKFGSPSPVWEPLVPSRMNYYALEVNTEKGIWPRMEEDFHESDVNFWFINMTA 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	128/514 (25%)
		Aes	<117..>221	CDD:223730	38/107 (36%)
cest-3	NP_510042.2	Abhydrolase	23..496	CDD:304388	125/506 (25%)
		Aes	<118..>254	CDD:223730	41/140 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157126
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740