Protein Alignment alpha-Est2 and cest-9.1

DIOPT Version :9

• Sequence 1: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001359584.1
• Gene: cest-9.1 / 181383
• WormBaseID: WBGene00007692
• Length: 614
• Species: Caenorhabditis elegans
• Alignment Length: 580
• Identity: 136/580 - (23%)
• Similarity: 218/580 - (37%)
• Gaps: 155/580 - (26%)

  Fly    34 ILDTKYGQVRGLQRKTVY--DKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLN-------C 89
            ::.|.||::||:   ||:  ||...:.|:.:|:||||||:|||..||.||.|.|:|:       |
 Worm    20 VIQTSYGKLRGI---TVWSNDKNHRYMFKSVPFAKPPVGNLRFAKPQNPESWSGILDASKYSPAC 81

  Fly    90 TTNRSKPM--QRNMLLGIVEGSEDCLHLNVYV--KALKSEKPLPVIVWIYGGGFQKGEA--SRDI 148
            .:|.|...  |::.       |||||::|::.  |.|.|:  .||||:.:||.:....|  ..|.
 Worm    82 MSNSSSTSTPQKHY-------SEDCLYINIFTSEKCLNSK--CPVIVYFHGGAYNLDSAIMFNDT 137

  Fly   149 YSPDYFMKKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNI 213
            :..|.:..:.||||....||...|.|......| :..|..|.|.|.||.::...|.:|.||...:
 Worm   138 FILDRYAAEDVVFVIPAVRLGVFGQLYFGPSDL-LSENLFLYDAVQALSFVHSEINYFGGDSKRV 201

  Fly   214 TLMGESAGSASVHVM---MTTEQTRGLFHKAIMQSGCALSEWVESPDNNWAFRLAQNLG-YKG-- 272
            |.||.|:|...|..:   ...:....||.:.|:.|...:..:.:...:| :|.:.:..| |.|
 Worm   202 TAMGHSSGGTIVDALGFSKLIDPGVKLFQQMIVLSATGMFGFYDMVVDN-SFAIVEKFGCYNGTK 265

  Fly   273 -DEKDADVLSFLSKVCARQIAAIDQDVINLDEVRSFLLFAFGPVIEPYETDHCVVPKRHKDLLSE 336
             |..:|::...|.  |.|||           :.|..||.                 :||   :.|
 Worm   266 DDRPNANIAEMLD--CMRQI-----------DGREMLLM-----------------QRH---MEE 297

  Fly   337 AWGNDIPVIVGGNSF-EGLFSYQLVRKDPWALKNFHNILPREVRETSSLE----------GQDLL 390
            ....|...::.|..| |.......::|.|.:....:.....|.|....:.          ...:.
 Worm   298 VDDRDFRSVLRGAPFLESNGKIADLKKSPPSRNLLYGTTEHEFRNVDHMNPYISGIFLDFDNPVA 362

  Fly   391 VRRLKQLYFNNEMQESME---------MFEALNIFS----------------------------- 417
            |.|    |::.::..::|         :|...:.||
 Worm   363 VAR----YYDEQLMANLETMINGDAAAIFICASTFSTAMANTGADVYLFETRQKPYSFHVSDMQY 423

  Fly   418 ----HRQIWHDTHRFILARQSYAPKTPTYLYRFDFDSPHF--------NQFRRLVCGDRIRGVA- 469
                ||:|:|.....||  .::..|......:....||.:        |.....|..|...|..
 Worm   424 FVGIHREIYHRPDMDIL--DTFYSKLLVNFTKMGVPSPEWAPLDPERMNYLELKVDSDMKEGPVM 486

  Fly   470 ----HADELSYLFYNII-----ASKLDKSS---MEYKTIERMVGMWTSFASSGNPNCPEL 517
                |..|:...|..::     .:|:.:|.   .|:..||..:..|.:      .|.||:
 Worm   487 LEGFHEKEMELWFGEMMEFDRNVTKIRQSQGLPPEHLDIETQLKYWET------TNKPEI 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	136/580 (23%)
		Aes	<117..>221	CDD:223730	35/107 (33%)
cest-9.1	NP_001359584.1	Abhydrolase	19..498	CDD:389770	126/530 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157194
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740