Protein Alignment alpha-Est2 and cest-26

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001368609.1
• Gene: cest-26 / 180715
• WormBaseID: WBGene00017478
• Length: 585
• Species: Caenorhabditis elegans
• Alignment Length: 573
• Identity: 166/573 - (28%)
• Similarity: 252/573 - (43%)
• Gaps: 96/573 - (16%)

  Fly    37 TKYGQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTTNRSKPMQRNM 101
            |:.|.|.|.:.|...|:| ...|.|||:||.|||||||:.|:..|.|.||..|.....:..|.:.
 Worm    46 TRNGLVEGFRIKIDDDRE-VDMFLGIPFAKAPVGDLRFKNPEHTEDWDGVKKCVRFGPRAPQADF 109

  Fly   102 L-----LGIVEGSEDCLHLNVYVKALKSEKPL----PVIVWIYGGGFQKGEASRDIYSPD----Y 153
            .     ||:.: |||||:|||:....|:|:..    ||:|:::||||....|.:  |..:    |
 Worm   110 FWERFTLGVGK-SEDCLYLNVFSPTWKAEEVSNGLHPVMVYVHGGGFLIDSAVK--YGDEGIAKY 171

  Fly   154 FMKKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGE 218
            ..:..||.|.|.|||..|||.|..|..  .|||.||.|..|||:|:..|:..|.|||..:|:.|:
 Worm   172 LCRHGVVVVTIQYRLGLLGFFSTGDQV--CPGNLGLWDMTMALQWVRDNVHAFGGDPRKVTVFGQ 234

  Fly   219 SAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESPDNNWAFRLAQNLGYK--GDEKDA---- 277
            |||..||.::..:..:|.|||:.:..:|....|| .:...|......:...|:  .|||.|
 Worm   235 SAGGVSVDLLSLSPHSRDLFHQVVPMAGNGECEW-STVGKNRLVNACREFAYRKCWDEKQARDEN 298

  Fly   278 ---DVLSFLSKVCARQI-------AAIDQDVINLDEVRSFLLFAFGPVIEPYETDHCVVPKRHKD 332
               .:|.||.....|:.       ..:|...|.||         ..|||....:|  .:||..::
 Worm   299 ASESMLEFLRTRKEREFEKRLLTRKGVDVSKIGLD---------LAPVIGSKPSD--FLPKSIEE 352

  Fly   333 LLSEAWGNDIPVIVGGNSFEGLFSYQLVRKDPWALKNFHNILPREVRETSSLEGQDLLVRRLKQL 397
            |..||...:|  :||....|||. :..:....:..|....:|...:.|.:. |..:.|....|::
 Worm   353 LRKEAPKKNI--MVGTCEHEGLL-FASLGPSNFDEKGIDKLLALLITEENH-EDFEALREEAKKM 413

  Fly   398 YF----NNEMQESMEMFEALNIFSHRQIWHDTHRFILARQSYAPK-----TPTYLYRFDFDSPHF 453
            |.    ::|..:.:.....:.::|...:.:.|:       :||.|     ...::|.||:.:|
 Worm   414 YLKKLSDDEDDKEVAARGYIQLYSDLFVNNGTY-------NYAEKMTKLGNKVFMYSFDYCNP-- 469

  Fly   454 NQFRRLVCGDRIRGVAHADELSYLF-----YNIIASKLDKSSMEYKTIERMVGMWTSFASSGNPN 513
            ..|..|......|...|..||:|:|     :|...::.|::.::.     |..|||:||..||||
 Worm   470 RSFGILSLRAPFRAATHCTELAYIFGVSIVFNYRYNESDRAMLDL-----MTKMWTNFAKYGNPN 529

  Fly   514 CPELGSA----KWEAVQLKENA------VEKCFNISHDLEMRDLPESDCLAVW 556
            .....|.    |||....:|..      .:||       ||:.:.:.:....|
 Worm   530 GQYEDSTVFDFKWEPTSKEEPTNFLAINEKKC-------EMQTVYQDNRAEFW 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	165/571 (29%)
cest-26	NP_001368609.1	COesterase	40..575	CDD:395084	165/571 (29%)