Protein Alignment alpha-Est2 and cest-2.3

DIOPT Version :9

• Sequence 1: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_506510.2
• Gene: cest-2.3 / 179918
• WormBaseID: WBGene00013873
• Length: 665
• Species: Caenorhabditis elegans
• Alignment Length: 594
• Identity: 147/594 - (24%)
• Similarity: 242/594 - (40%)
• Gaps: 141/594 - (23%)

  Fly    26 RLSTGHTV---ILDTKYGQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVL 87
            :|||| |:   ||:..|... |.|..||        |.||||.:||:|:||||.|:..:.|:|||
 Worm    21 QLSTG-TIEGKILNATYSPF-GNQTATV--------FLGIPYVEPPIGELRFRKPRLLKSWEGVL 75

  Fly    88 NCTTNRSKP-----MQRNMLLGIV-EGSEDCLHLNVYV-KALKSEKPLPVIVWIYGGGF--QKGE 143
            .  |...||     .::....|.| |.|||||:.||:. :.....|...|::.::||..  :.|.
 Worm    76 E--TKDYKPACMSYWRKTFKNGFVGEISEDCLYANVFTNQYCLQNKNCSVMIVVHGGRLVCESGS 138

  Fly   144 ASRDIYSPDYFMK------KPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQN 202
            |    :.|:.|:.      :.:|.|..||||...||........|.  |..:.|.:.|::|:.:.
 Worm   139 A----FKPEIFINNFVGQDRNIVVVTFNYRLGVFGFGVFNGETGDT--NVAMYDMLEAVKWVRKE 197

  Fly   203 IAHFNGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESPDNNWAFRLAQN 267
            |..|.|:.:.||:.|.|||:..:....::..::||.|:.|:.| ..|.:..:|.:......:|||
 Worm   198 IDQFGGNKDRITMAGHSAGAGLIVDFTSSTLSKGLLHQQIVMS-APLQDISKSANFKGMTIVAQN 261

  Fly   268 LGYKGDEKDADVLS--FLSK--VCARQIAAIDQDVINLD-EVRSFLLFAFGPVIEPYETDHCVVP 327
            :|....|.....||  .::|  :|.:..:|  ||:::.. .::....|.||.            |
 Worm   262 VGCIPKEYGFRKLSKTQINKTYLCLQNKSA--QDLLHAQLSMQQNSTFYFGS------------P 312

  Fly   328 KRHKDLLSEAWGNDIPVIVGGNSFEGLFSYQLVRKDPWALKNFHNILPREVRETSSLEGQDLLVR 392
            :...|.::     |.|        :.||::..:    :.:..|......|:|:  ||...|....
 Worm   313 RVDGDFIT-----DYP--------DNLFNFNTI----YPINTFIGTTTGELRD--SLYITDPKND 358

  Fly   393 RLKQLYFNNEMQE-SMEMFEALNIFSHR-----------QIWHDTHRFI-----LARQSYAPKTP 440
            |:|:....|..:. ..|:||....|:.:           |...|...|.     :|.......:.
 Worm   359 RIKEQLLKNMCEHVGYELFEKPEEFTKKCGNYYKNGTDAQFLSDDMEFYSGAIKVANAHKRANSK 423

  Fly   441 TYLYRFDF-------------DSPHFNQFRRLVCGDRIRGVAHADELSYLFYNIIASKLDKSSME 492
            .::|.:|:             .|||                 |:::|.|.|.   .|:....:.:
 Worm   424 VFMYSYDYKGAGTAFHKYLEAPSPH-----------------HSEDLIYTFG---TSRGPFVAKD 468

  Fly   493 YKTIERMV-GMWTSFASSGNPNCPELGSAKWEAVQLKENAVEK--CFNISHDLE-----MRDLPE 549
            | .|||:. ||..:|.:..:|: |.      :..|.::...||  .|.|..|..     |:|...
 Worm   469 Y-VIERIYSGMLANFINFEDPS-PS------KTQQWRQYTQEKREYFLIDFDKNFTMPGMKDHYY 525

  Fly   550 SDCLAVWDT 558
            :..|..|.|
 Worm   526 TRALDFWST 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	132/544 (24%)
		Aes	<117..>221	CDD:223730	29/112 (26%)
cest-2.3	NP_506510.2	Abhydrolase	20..532	CDD:389770	145/590 (25%)
		CemA	<550..>647	CDD:383495

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157038
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740