Protein Alignment alpha-Est2 and cest-2.1

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_506508.2
• Gene: cest-2.1 / 179916
• WormBaseID: WBGene00013875
• Length: 675
• Species: Caenorhabditis elegans
• Alignment Length: 592
• Identity: 151/592 - (25%)
• Similarity: 256/592 - (43%)
• Gaps: 137/592 - (23%)

  Fly    26 RLSTGHTV---ILDTKY---GQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQ 84
            :|||| |:   ||.:.|   |...|:            .|.|||:.:||.|:||||.|:||.||.
 Worm    22 QLSTG-TIEGKILTSTYSPLGNHTGI------------GFLGIPFVEPPAGNLRFRKPRPPIPWD 73

  Fly    85 GVLN-------CTTNRSKPMQRNMLLGIVEGSEDCLHLNVYV-KALKSEKPLPVIVWIYGGGFQK 141
            |:|.       |.:: :|...:|.:.|.:  |||||:.||:. :.....|...|::.::||....
 Worm    74 GILETKEYKPACMSD-AKKTYKNGVGGPI--SEDCLYANVFTNQYCMKRKNCSVMIVVHGGRILT 135

  Fly   142 GEASRDIYSPDYFMK------KPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWIS 200
            ..||  .::|:..:.      :.:|.|..||||...||..|...|.|  .|.|:.|.:.|::|..
 Worm   136 ESAS--AFNPEILVNNFVGQGRNIVVVTFNYRLGTFGFGVLNGEKGD--SNVGMFDMLEAVKWTR 196

  Fly   201 QNIAHFNGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESPDNNWAFRLA 265
            :.:.:|.|:.:.:|::|.|||.:.|....::..::|:.::.|:.|| ||.:..:..:......:|
 Worm   197 KEVHNFGGNKDKLTMVGHSAGGSLVGAFTSSPLSKGMLNQQIIMSG-ALYQMGKLANFKGMTAMA 260

  Fly   266 QNLGYKGDEKDADVLSF--LSKV-------CARQIAAIDQDVINLDEVRSFLLFAFGPVIEPYET 321
            |..|..     .:|..|  ||:|       |.|.|:|  |:|:   :.:.::|        ...|
 Worm   261 QKAGCL-----PEVFGFRKLSQVRIDKTYSCLRNISA--QEVL---DAQLWVL--------QNTT 307

  Fly   322 DHCVVPKRHKD---LLSE-----AWGNDIPVIVGGNSFEGLFSYQLVRKDPWALKNFHNILPRE- 377
            .:..||  |.|   ||:.     |.|...|:    ||..|..:.:|  :||..:.:..|...:|
 Worm   308 YYISVP--HIDGEFLLNYSDEILASGTIHPI----NSMIGTTTAEL--RDPIYINDLKNADKKEE 364

  Fly   378 -VRETSSLEGQDLLV------RRLKQLYFNNE----MQESMEMFEALNIFSHRQIWHDTHRFILA 431
             ::......|.:|..      |:.::.|.|.:    :.:.||.::.               .|..
 Worm   365 LLKNLCEHIGYELYTEPEEFSRKCQKFYGNGDDAQFLADDMEFYDG---------------SIKV 414

  Fly   432 RQSYAPK-TPTYLYRFDFD--SPHFNQFRRLVCGDRIRGVAHADELSYLFYNIIASKLDKSSMEY 493
            ..::|.| |..::|.:|:.  .|.|.::.      :.....|:::|.|:|.   .|:.:.:..:|
 Worm   415 ANAHASKNTKVFMYSYDYKDAGPAFKKYA------QAPPPHHSEDLIYVFG---TSRGNFTEKDY 470

  Fly   494 KTIERMVGMWTSFASSGNPNCPELGSAKWEAVQLKENAVEK--CFNISHDLEM-----RDLPESD 551
            ...:...||:..|.:.|||:..:  ..||     ||.:.||  .|.|..|...     ||...|.
 Worm   471 VIEQIYSGMFADFVNFGNPSPSK--EQKW-----KEYSPEKREYFLIDFDKNFTMPGTRDGYYSR 528

  Fly   552 CLAVWDT 558
            .|..|.|
 Worm   529 ALEFWST 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	144/577 (25%)
cest-2.1	NP_506508.2	COesterase	18..533	CDD:395084	149/588 (25%)