Protein Alignment alpha-Est2 and cest-17

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_505114.1
• Gene: cest-17 / 179198
• WormBaseID: WBGene00019477
• Length: 571
• Species: Caenorhabditis elegans
• Alignment Length: 593
• Identity: 164/593 - (27%)
• Similarity: 256/593 - (43%)
• Gaps: 135/593 - (22%)

  Fly    37 TKYGQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTTN-RSK--PMQ 98
            |.||.:.|.:.|:......|..|.||.|..||....||:.|:|.|.|..:.:..|: |:.  |..
 Worm    26 TPYGPIVGFEHKSTVTGSKYHVFLGIRYGNPPDHIYRFQKPEPVEKWPHINHDATHFRASCIPSL 90

  Fly    99 RNMLLGIVEGSEDCLHLNVYVKALKSEKPLPVIVWIYGGGFQKGEASRDIY--SPDYFMKKPVVF 161
            |:.|...|..|||||.||:.......||.|||:|:|:|||||.|:.|...|  :.|.|:.|.::|
 Worm    91 RSELEEQVNYSEDCLFLNIVTPPDAKEKKLPVLVFIHGGGFQFGDTSMIGYQKAADNFVSKDIIF 155

  Fly   162 VAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSASVH 226
            |:|.|||..|||.:..|.  ::|||.||.||.:||:::.:.:..|.|||:.|||.|.|||:|||.
 Worm   156 VSIQYRLGPLGFFTTGDS--EIPGNMGLWDQTLALQFLHEVLPDFGGDPDRITLAGHSAGAASVS 218

  Fly   227 VMMTTEQTRGLFHKAIMQSGCALSEWVESPDNNW---AFRLAQNLGYKGDEKDADVLSFLSKVCA 288
            .::.:..:..||.:||..||...||  .:.|.|.   :.:||:..|.  .::|:..|    :.|.
 Worm   219 ALLYSPHSDHLFSQAIQLSGSIFSE--SNLDRNVVDDSRKLAKAAGC--PQEDSKEL----RDCI 275

  Fly   289 RQIAAIDQDVINLDEVRSFL----LFAFGPVIE----PYETDHC--VVPKRH--KDLLSEAWGND 341
             :|..:|:.:..::.:...|    ...|.|..:    ||:.:..  ..||:.  :.|:|...|..
 Worm   276 -EIRTVDELLDAMESIGELLPGPRTKKFHPYFDKDFFPYDIEKMSRKAPKKRTMQGLVSLESGLS 339

  Fly   342 IPVIVGGNSFEGLFSYQL-----VRKDPWALKNFHNILP--------REVRETSSLEGQDLLVRR 393
            :           |:..:|     |.|:.|:..:..|::.        .:...|:|.....|
 Worm   340 V-----------LYPVKLAKLLGVPKESWSTYSKDNLVDFIRSQVAVEQEFGTASARFSGL---- 389

  Fly   394 LKQLYFNNEMQESMEMFEALNIFSHRQIWHDTHRFILARQSYAPKT------------PTYLYRF 446
            :::.|.:..|..:...:  ||.|::          :|:...|...|            .||||..
 Worm   390 VEEFYLSGPMTGNSSFY--LNAFAN----------LLSDLQYNIPTLHEVELKLQHGWDTYLYII 442

  Fly   447 DFDS------PHFNQFRRLVCGDRIRGVAHADELSYLF-YN----IIASKLDKSSMEYKTIERMV 500
            |:||      .|           .|:|..||.||.||| :|    |..:..||....|     .|
 Worm   443 DYDSETTKDPTH-----------PIKGPFHASELRYLFNFNGMDTIPFNDKDKKFENY-----FV 491

  Fly   501 GMWTSFASSGNPNCPEL-----------------------GSAKWEAVQLKENAVEKCFNISHDL 542
            ....:|.::|.|:...|                       .|.:.||.:|.::.:.|  .:..||
 Worm   492 NAIVNFINTGTPSTKALLWPAVSKSQPFANLLLNDKPSVQTSFRQEAYELWQSDIAK--TVGADL 554

  Fly   543 EMRDLPES 550
            ..:.||.|
 Worm   555 MKKRLPAS 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	164/593 (28%)
cest-17	NP_505114.1	COesterase	22..542	CDD:395084	157/569 (28%)