Protein Alignment alpha-Est2 and cest-34

DIOPT Version :9

• Sequence 1: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001360105.1
• Gene: cest-34 / 179057
• WormBaseID: WBGene00019652
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 529
• Identity: 164/529 - (31%)
• Similarity: 255/529 - (48%)
• Gaps: 84/529 - (15%)

  Fly    34 ILDTKYGQVRGLQRKTVY---DKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTT--NR 93
            :|:|..|.|.|    .:|   |||.: .:.|:||||||.|::||..|.|.:.|....:||.  .|
 Worm    16 VLNTSCGPVLG----NLYRHGDKEVH-GYLGMPYAKPPTGEMRFAKPVPADDWTETRDCTKYGPR 75

  Fly    94 SKP----MQRNMLLGIVEGSE-DCLHLNVYVKALKS---EKPLPVIVWIYGGGFQKGEASRDIYS 150
            ..|    :::.|.:...|..| :.|.:||:|...:|   :...||:|:::||||:. .:||:..
 Worm    76 CPPSGQGLEKGMFVNPDEPDEANGLSVNVFVPGWESSEYKNARPVMVYVHGGGFEI-SSSREFC- 138

  Fly   151 PDYFMK-----KPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDP 210
             ||.:.     |.|:.|.:||||..|||.:..|..  .|||.||.||.:||:|:.::||.|.|||
 Worm   139 -DYSISSTLPMKDVILVTMNYRLGILGFFTTGDEV--CPGNFGLWDQTLALQWVQKHIASFGGDP 200

  Fly   211 NNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESPDNNWAFRLAQNLGYKGDEK 275
            ||:||.|:|||.|.|.::..:..:|.||.|.:..||.|:.|        :|.|.|:|..:..|
 Worm   201 NNVTLFGQSAGGACVDLLTLSPHSRDLFQKVVPMSGSAMCE--------FAMRTAENEAHVFD-- 255

  Fly   276 DADVLSFL------SKVCARQIAAIDQDVINLDEVRSFLLFAFGPVIEPYETDHCVVPKRHKDLL 334
              |:|:.|      ||.....:.::..|.|......::....|..:...|:.|  ..||...:|.
 Worm   256 --DILARLGFTGSGSKERLEFMRSLPCDKITGKTGYTYKQSGFMSLCPNYDGD--FFPKPLDELR 316

  Fly   335 SEAWGNDIPVIVGGNSFEG-LFSYQLVRKDPWALKNFHNILPREVRE------TSSLEGQDLLVR 392
            .:|....:...:.||  || ||::.  |..|:  |::.::|..::.|      ...:||   :.:
 Worm   317 KDASKRILMTGIVGN--EGLLFAFD--RNTPY--KDYTDLLRLKIEEDYKEDVVDDVEG---IRK 372

  Fly   393 RLKQLYFNN--EMQESMEMFEALNIFSHRQIWHDTHRFILARQSYAPKTPTYLYRFDFDSPHFNQ 455
            .:.:.|..|  |..|...|.:|.. |....|:|...| ..|:.:.......:||.||:.:|  :.
 Worm   373 EIFEYYTKNISEGDEEAIMRKAAE-FVGDSIFHTGVR-ATAQNAAEHGDEVWLYNFDYCNP--DG 433

  Fly   456 FRRLVCGDRIRGV------AHADELSYLFYNIIASKLDKSSMEYKTIERMVGMWTSFASSGNPNC 514
            |..|      :|.      .|..||.|||.:.|.||.:.:..|.|.:::...|:.:||..||||
 Worm   434 FAPL------KGYLPYIEPTHGMELRYLFGDGIISKFEPTEEELKMLDKFTTMFANFAKYGNPN- 491

  Fly   515 PELGSAKWE 523
             |.||:.||
 Worm   492 -ETGSSAWE 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	162/527 (31%)
		Aes	<117..>221	CDD:223730	47/111 (42%)
cest-34	NP_001360105.1	COesterase	15..530	CDD:365897	164/529 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm14726
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.710