Protein Alignment alpha-Est2 and cest-24

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_504613.1
• Gene: cest-24 / 179017
• WormBaseID: WBGene00020891
• Length: 658
• Species: Caenorhabditis elegans
• Alignment Length: 568
• Identity: 168/568 - (29%)
• Similarity: 265/568 - (46%)
• Gaps: 97/568 - (17%)

  Fly    27 LSTG--HTVILDTKYGQVRGLQRKT----VYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQG 85
            |.:|  ...|:..:.|.:.|.:.||    :.|     .|.|||||:||||:|||:.||||:.|:|
 Worm    88 LKSGKSENAIVRVQQGLLEGFRVKTAKGDLCD-----VFHGIPYAEPPVGELRFQKPQPPKAWEG 147

  Fly    86 VLNCT--TNRS--KPMQRNMLLGIVEGSEDCLHLNVYVKALKSEKPLPVIVWIYGGGFQKGEASR 146
            :..|.  .|||  |.|..:..|.....|||||:|||:...::.:|..||:.:|:|||:....|.|
 Worm   148 IRKCNKYPNRSIHKEMPWDKALPSANQSEDCLYLNVFAPKIREDKKYPVLFYIHGGGYVMDSAER 212

  Fly   147 DIYSPDYFMK----KPVVFVAINYRLAALGFLSLKDPKLDV-PGNAGLKDQVMALRWISQNIAHF 206
              |:.....|    :.::.|..:|||..|||||..|   || |||.||.|.:.|:||:..||:.|
 Worm   213 --YTAKNICKLLVSREIIVVTFHYRLGFLGFLSTGD---DVCPGNYGLFDMLEAMRWVHANISSF 272

  Fly   207 NGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESPDNN-------WAFRL 264
            .|||.||||.|:|||:|:..::..:..|:|||.:.|:..|.:...|..:.:::       ||.||
 Worm   273 GGDPENITLSGQSAGAAAADLLSFSPLTKGLFKRKIVMGGNSYCHWATTSNHDIREYCKKWAKRL 337

  Fly   265 A--QNLGYKGD-EKDADVLSFLSKVCARQIAAIDQDVINLDEVRSFLLF-----AFGPVIEPYET 321
            .  ..|.|... |:..|:.:|.:        .:....:.:....|..:|     ...|||
 Worm   338 GWKPQLNYANKREESVDIFNFFN--------GLPTSKLGMTMFFSNTIFKECQLPLAPVI----- 389

  Fly   322 DHCVVPKRHKDLLSEAWGNDIPVIVGGNSFEGLF--SYQLVRKDPWALKNFHNILPREVR----- 379
            |..::|...| :|.|. ...:|.:|||..:|.|.  :..|:|.....:.:..::|.|:.|
 Worm   390 DGEILPHDLK-VLRET-QEHVPSLVGGGEYEALLFCAIGLLRGTEKEINSAIDVLSRKNRLSRSK 452

  Fly   380 ---ETSSLEGQDLLVR---RLKQLYFNNEMQESMEMFEALNIFSHRQIWHDTHRFILARQSYAPK 438
               .|..:.|....:|   :.::::|...:.:         ||::    :..:||:  |......
 Worm   453 IEAMTEKVYGDSPALRADSKARKMFFVQLISD---------IFAN----YGNYRFM--RDCQQRG 502

  Fly   439 TPTYLYRFDFDSPH-FNQFRRLVCGDRIRGVAHADELSYLF-YNIIASKLDKSSMEYKTIERMVG 501
            ...|.|.||..|.. :...:.:|   ...|..|..|||||| .|.:::.|..:    ||.:.:.|
 Worm   503 VECYGYSFDHQSKQMWGWLQHVV---PFTGGTHTSELSYLFDCNYMSAPLGMN----KTDKVVSG 560

  Fly   502 M----WTSFASSGNPNCPELGSAKWEAVQLKENAVEKCFNISHDLEMR 545
            |    :|:|...|.||.|.....|||.:...:..: |..:|..:.||:
 Worm   561 MTADYFTNFVKFGTPNGPNSQLPKWERISPDDEHM-KLISIKPEPEMK 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	166/559 (30%)
cest-24	NP_504613.1	COesterase	97..608	CDD:395084	166/559 (30%)