Protein Alignment alpha-Est2 and cest-32

DIOPT Version :9

• Sequence 1: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_504397.1
• Gene: cest-32 / 178909
• WormBaseID: WBGene00016862
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 552
• Identity: 157/552 - (28%)
• Similarity: 242/552 - (43%)
• Gaps: 90/552 - (16%)

  Fly    34 ILDTKYGQVRGLQRKTVY--DKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNC-----TT 91
            :|:...|.|.|    .:|  |.:....:.|||:||.|:.:|||:.|...|.|...|||     ..
 Worm    16 VLNASCGPVIG----NIYRHDDKIVNGYLGIPFAKAPICELRFKKPVEAEKWTKPLNCHKYGPGC 76

  Fly    92 NRSKPMQRNML-LGIVEGSED-CLHLNVYVKALKSEK---PLPVIVWIYGGGFQKGEASR-DIYS 150
            .:|..|..|:| .|..|.:|| ||:||::..:.|||:   .||::|:.:||||:.|.:|. |.||
 Worm    77 PQSGHMISNLLPPGYREFAEDNCLNLNIFAPSWKSEEFPNGLPIMVYFHGGGFEIGFSSMFDDYS 141

  Fly   151 PDYFMK-KPVVFVAINYRLAALGFLSLKDPKLDVP-GNAGLKDQVMALRWISQNIAHFNGDPNNI 213
            ....:. |.|:.|..|||:..|||::..|   :|. ||.||.||.:||:|:.::|..|.|:||.:
 Worm   142 LSGTLPLKDVIVVTANYRVGPLGFMTTGD---EVSRGNYGLWDQTLALKWVQEHIKSFGGNPNIV 203

  Fly   214 TLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESPDNNWA--FR-LAQNLGYKGDEK 275
            |:.|.|||..|..::..:..:..|||:.:..||.|..|:........|  || .|::.||:|::.
 Worm   204 TVCGTSAGGVSAGLLALSPHSNKLFHRFMAMSGSAFCEFSIRTKEQEAEIFRNFAKHHGYEGEDS 268

  Fly   276 DADVLSFLSKVCARQIAAIDQDVINLDEVRSFLLFAFGPVIEPYETDHCVVPKRHKDLLSEAWGN 340
            :    |.|....::.::...:......:...||.|     |..::.|  ..||...:|..||...
 Worm   269 E----SLLEWYKSQPLSKFQETATFEKKASGFLTF-----IPNFDGD--FFPKPFDELSREAPKL 322

  Fly   341 DIPVIVGGNSFEG---LFSYQLVRKDPWALKNFHNILPREVRETSSLEGQDL------LVRRLKQ 396
            |....|  :.:||   |..:|..|.|...:|              |..|.|:      :.:|:.:
 Worm   323 DAMATV--DEYEGLGFLTMFQSRRNDMDIIK--------------SSFGSDVVENAVDVQKRIME 371

  Fly   397 LYFNNEMQESMEMFEALNIFSHRQIWHDTHRFILARQSYAPKTPTYLYRFDF-----DSPHFNQF 456
            .|..|..:...:..|...|......|.:.......:.|....:..||..||:     :.|:...|
 Worm   372 FYMKNIDKNDDKAVEKRLIQLISDSWFNIGALETVKTSTKYGSNAYLGSFDYYNMGSNDPYATWF 436

  Fly   457 RRLVCGDRIRGVAHADELSYLFYNIIASKLDKSSMEYKTIERMVGMWTSFASSGNP---NCPELG 518
                   ..:...|..||.|:....: .|......|:|.|:.|..:..:|...|||   |.|||
 Worm   437 -------PFKAANHGSELKYMLGEGM-GKFSPIEEEFKVIDMMGTLTANFVKYGNPNGINGPEL- 492

  Fly   519 SAKWEAVQLKENAVEK---CFNISH-DLEMRD 546
               |     |:...||   .|.|.: ..||||
 Worm   493 ---W-----KKYTPEKPYSYFKIDYPKSEMRD 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	147/523 (28%)
		Aes	<117..>221	CDD:223730	43/109 (39%)
cest-32	NP_504397.1	COesterase	15..516	CDD:278561	155/550 (28%)
		Aes	<104..>227	CDD:223730	46/125 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157252
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.640