Protein Alignment alpha-Est2 and ges-1

DIOPT Version :9

• Sequence 1: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_503411.1
• Gene: ges-1 / 178633
• WormBaseID: WBGene00001578
• Length: 562
• Species: Caenorhabditis elegans
• Alignment Length: 597
• Identity: 164/597 - (27%)
• Similarity: 267/597 - (44%)
• Gaps: 140/597 - (23%)

  Fly    34 ILDTKYGQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTTNRS--KP 96
            |::|.||:|.|::    |:....|.  .||:|||||.||||..|..|:||:.|...|..|:  .|
 Worm    19 IVETNYGKVEGIE----YEGAEVFL--AIPFAKPPVDDLRFEKPVAPDPWEDVYPATQYRNDCTP 77

  Fly    97 MQRNMLLGIVEGSEDCLHLNVYVKALKSEKPLPVIVWIYGGGFQKGEASRDIYSPDYFMKK---- 157
            ..|.:........||||.||: :|..|:|| |||:.||:|||::.|.||:..|  ::|.|:
 Worm    78 HYRLVAQFSSYSGEDCLTLNI-IKPKKAEK-LPVLFWIHGGGYEIGSASQHGY--EFFAKRYASQ 138

  Fly   158 PVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGS 222
            .|:...:.|||..:||.|  :...||.||.||.||..||.::..||.:|.||||.||:.|.|||:
 Worm   139 GVIVATVQYRLGFMGFFS--EGTSDVQGNWGLFDQAAALEFVKSNIENFGGDPNQITIWGYSAGA 201

  Fly   223 ASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESPD-NNWAFRLAQNLG--YKGDEKDADVLSFLS 284
            |||..:..:..||..:.|||:.|..:...|...|: ...:.:||:.||  :.|           :
 Worm   202 ASVSQLTMSPYTRDSYSKAIIMSASSFVGWATGPNVVETSKQLAEILGCPWPG-----------A 255

  Fly   285 KVCARQIAAIDQDVINLDEVRSFL-----LFAFGPVIEPYETDHCVVPKRHKDLLSEAWGNDIPV 344
            |.|.::.:.  .::.:..||:.:.     :..:.|||     |...:.|..::|:.|:...  |.
 Worm   256 KECMKKKSL--HEIFDAIEVQGWTTGTIDILRWSPVI-----DGDFMTKNPEELIKESPVK--PT 311

  Fly   345 IVGGNSFEGLFSYQLVRKDPWALKNFHNIL------PREVRETSSLEGQDLLVRRLKQLYFNNEM 403
            ::|.::.||  ||       :|..|...::      |.::.:.......:::.|:   |.:||..
 Worm   312 LIGMSNKEG--SY-------FAALNMGRVIADFGLSPEDMPKVDEEFISEIIGRK---LLYNNRY 364

  Fly   404 QESMEMFEALNIFSHRQIWHDTHRFILARQSYAP------------------------------- 437
            .|:.|           ::|:|...|.:.:...|.
 Worm   365 GENRE-----------KVWNDILDFYVKQGKPAEVKDLNGFYVDRYSELLSDITFNVPILREITS 418

  Fly   438 ----KTPTYLYRFDFDSPHF--NQFRRLVCGDRIRGVAHADELSYLFYNIIASKLDKSSMEYKTI 496
                |||.:.||.|    |:  |.:::.: .::.||..||:|..|||...:.:|:|........|
 Worm   419 RVERKTPVWTYRMD----HYDKNIWKKHI-PEQARGSPHANEYHYLFDMPVMAKIDMKKEPDSWI 478

  Fly   497 ER-MVGMWTSFASSGNPNCPELGSAKWEAV---------QLKENAVEKCFNISHDLEMRDLPESD 551
            :. ::.|..|||.:|   .|::...:|..|         .::.:.|    :|.|.|      ..:
 Worm   479 QNDLIDMVISFAKTG---VPQIEDVEWRPVSDPDDVNFLNIRSDGV----SIEHGL------FQE 530

  Fly   552 CLAVWDTFYPRE 563
            .||.|:....||
 Worm   531 PLAFWNELRQRE 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	153/546 (28%)
		Aes	<117..>221	CDD:223730	46/107 (43%)
ges-1	NP_503411.1	COesterase	18..535	CDD:278561	161/588 (27%)
		Aes	<100..>211	CDD:223730	51/115 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm14771
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.710