Protein Alignment alpha-Est2 and cest-6

DIOPT Version :9

• Sequence 1: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_501070.1
• Gene: cest-6 / 177459
• WormBaseID: WBGene00020688
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 543
• Identity: 114/543 - (20%)
• Similarity: 192/543 - (35%)
• Gaps: 172/543 - (31%)

  Fly    34 ILDTKYGQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCT-------- 90
            ::.|..|.:.|.|..:      |..|:.||:||||:|.|||:.|...|.|:|:||.|
 Worm    25 VITTSLGSINGNQIGS------YQTFKKIPFAKPPIGKLRFQKPMAAEKWEGILNATEYGPACMS 83

  Fly    91 -TNRSKPMQRNMLLGIVEGSEDCLHLNVY-VKALKSEKPLPVIVWIYGGG--FQKGEASRDIYSP 151
             ::.||..|:.:       .|||||:|:: .....|.|...|:.:::||.  :.......|.|..
 Worm    84 NSSTSKSPQKWI-------DEDCLHINIFTTDTCLSSKNCSVVFYVHGGELVYDSAVMFEDKYLF 141

  Fly   152 DYFMKKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLM 216
            |.|..:.|:.|...:||.......::|..: .|.|..|.|.::||.::...|.:|.|..:.:|..
 Worm   142 DTFSSRDVILVIPAFRLGLFSHFVVEDQNV-APNNLALYDILLALEFVKSEIHNFGGSSDRVTAF 205

  Fly   217 GESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESPDNNWAFRLAQNLGYKGDEKDADVLS 281
            |.|.|...|.||                                ||         ..|.:.|:..
 Worm   206 GHSYGGHVVSVM--------------------------------AF---------STEINTDLSY 229

  Fly   282 FLSKVCARQIAAIDQDVINLDEVRSFLLFAFGPVIEPYETDHCVVPKRHKDLLSEAWGNDIPVIV 346
            |...:|...:...|.....:::...|:.:|           :|.||   :||.|..
 Worm   230 FQRVICMSSVNVWDSLEFEIEKTMRFIQYA-----------NCSVP---QDLKSRM--------- 271

  Fly   347 GGNSFEGLFSYQLVRKDPWALKNFHNILPRE-VRETSSLEGQ------DLLVRR-LKQLYFNNEM 403
              .|||         :|.:.::...:|...| :|...|||.:      .|::|. |.|.....:.
 Worm   272 --TSFE---------QDSYMMECLQDIDSMELLRIQRSLEDEGHPIYSGLVLREPLIQNVLVQDF 325

  Fly   404 QESMEMFEALNIFSHRQI--WHDTHRFI--LARQSY---------------------APKT---- 439
            .|..:....|...:::::  :|..|..:  |..::|                     |.:|
 Worm   326 YEKPKNIPTLTGCTYKELDKFHAYHNIVETLGYENYKECDDKYRDDRKYGRFDLNKHADETFGIL 390

  Fly   440 ---------------PTYLYRFDFDSPHFNQFRRLVCGDRIRGVAHADELSYLFYNIIASKLDKS 489
                           |||.|.:.:.                :..:|.|:|||:   :.....:|.
 Worm   391 AQTKLKVDKQLDKGIPTYFYEYSYP----------------KHPSHTDDLSYI---MGVHAFEKD 436

  Fly   490 SMEYKTIERMVGMWTSFASSGNP 512
            ..|....:....|:.:|...|.|
 Worm   437 ENEIHLAKSYQEMFMNFVKFGEP 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	114/543 (21%)
		Aes	<117..>221	CDD:223730	26/106 (25%)
cest-6	NP_501070.1	Abhydrolase	25..500	CDD:389770	114/543 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156942
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740