Protein Alignment alpha-Est2 and cest-12

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_499576.4
• Gene: cest-12 / 176642
• WormBaseID: WBGene00013540
• Length: 850
• Species: Caenorhabditis elegans
• Alignment Length: 238
• Identity: 83/238 - (34%)
• Similarity: 121/238 - (50%)
• Gaps: 23/238 - (9%)

  Fly    33 VILDTKYGQVRGLQRKTVYDKEPYF-----AFEGIPYAKPPVGDLRFRAPQPPEPWQGVL-NCTT 91
            |.:....|.|:|.|.....|:...:     ||.||||.:.|||:||.:.|||...:...| :.|.
 Worm    35 VTVSCSQGSVQGRQVNLGNDQSQLYSGQANAFTGIPYCQAPVGNLRLQPPQPLNQFNTTLHDATY 99

  Fly    92 NRSKPMQRNMLLGIVEG--SEDCLHLNVYV-KALKSEKPLPVIVWIYG-GGFQKG----EASRDI 148
            .|.|..|.|     ..|  :||||:||||. :|..:...|.|:|.|.| .||..|    ...:.|
 Worm   100 FRPKCPQLN-----AGGPTNEDCLYLNVYTPQAGNTNANLSVLVLIDGSNGFSNGGCDQNQEKGI 159

  Fly   149 YSPDYFMKKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNI 213
            .|  ..:::.:|.|.:.||:.||||.:....  .|..|.|:.|||.|:|||...|.:|.|:||.|
 Worm   160 IS--NLVQRQIVVVTMQYRIGALGFFTTYTN--SVQSNLGMLDQVQAMRWIKTEIVNFGGNPNQI 220

  Fly   214 TLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESP 256
            |:.|:..|:.:|.....:..::.||::||:|||...|.:..:|
 Worm   221 TVAGQDDGACAVSAHCLSPMSQNLFNQAIVQSGSVYSCYNPTP 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	82/237 (35%)
cest-12	NP_499576.4	alpha/beta hydrolases	40..>400	CDD:473884	82/233 (35%)
		alpha/beta hydrolases	<678..774	CDD:473884