Protein Alignment alpha-Est2 and ace-4

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_496962.1
• Gene: ace-4 / 175074
• WormBaseID: WBGene00000038
• Length: 602
• Species: Caenorhabditis elegans
• Alignment Length: 555
• Identity: 157/555 - (28%)
• Similarity: 234/555 - (42%)
• Gaps: 114/555 - (20%)

  Fly    31 HTVILDTKYGQVRGLQRKTVYDKEPYF------AFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNC 89
            |.|:|:||.|.::|        .|.:|      .|.|:|:|:|.|.|.|||.|:..:.|:|:.:.
 Worm    25 HPVVLETKLGDIKG--------TEFFFLSKKIRTFFGVPFAEPAVEDFRFRKPREKKQWRGLYDA 81

  Fly    90 TTNRSKPMQ-----------RNMLLGIVEGSEDCLHLNVYVKALKSEKPLPVIVWIYGGGFQKGE 143
            |...:...|           ..|.....:.|||||:||::..|  ....|.|:||.:||||..|.
 Worm    82 TKPANACFQTRDNYNTSFWGSEMWNANTQISEDCLYLNIWAPA--DAYNLTVMVWFFGGGFYSGS 144

  Fly   144 ASRDIYSPDYFMK-KPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFN 207
            .|..||....... :.|:.|.|||||...|||.|..|  |.|||.||.||.:||.|:.|||..|.
 Worm   145 PSLSIYDGKALTSTQNVIVVNINYRLGPFGFLYLGHP--DAPGNMGLLDQQLALHWVRQNIVSFG 207

  Fly   208 GDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESPDNNWAFRLAQNLGYKG 272
            |:|:.:.:.|:|||:||:...:....:||||..||:|||        |.:|.||.    |..::.
 Worm   208 GNPDKVAVFGQSAGAASIVAHLIAPGSRGLFKNAILQSG--------SLENTWAI----NSPFRA 260

  Fly   273 DEKDADVLSFL---------SKVCARQIAAIDQDVINLDEVRSFLLFAFGPVIEPYETDHCVVPK 328
            .:|...:|..:         |..|.|.::.....:...:...::|.|.|            |:..
 Worm   261 KQKSEKLLELVGCNKTTVDTSMACLRLVSPEQLSLSTWNISLTYLEFPF------------VIVS 313

  Fly   329 R----------HKDLLSEAWGNDIPVIVGGNSFEGLF--SYQLV----RKDPWALK--NFHNILP 375
            |          |..|....:..|:.:::|.|..||.:  .|||.    :.||..|.  .|..::.
 Worm   314 RDKHFFGHLDAHAALREGDFNRDVNLMIGMNKDEGNYWNIYQLPQFFDKADPPELNRTEFDFLID 378

  Fly   376 REVRETSSLEGQDLLVRRLKQLYFNNEMQE----------SMEMFEALNIFSHRQIW-HDTHRFI 429
            |    |.|:: .|::....|.:|.:....:          .|........||...:| .|..|.|
 Worm   379 R----TFSIQ-PDIIRSAAKYIYSDPNCTDHGRKTRFYAGQMNQIVGDYFFSCDSLWLADQFRSI 438

  Fly   430 LARQSYAP-KTPTYLYRFDFDSPHFNQFRRLVCGDRIRGVAHADELSYLFYNIIASKLDKSSMEY 493
            ...:|.:| :.|..::.:     ||.|........:..|..|..|:.|:| .|..|    .|..|
 Worm   439 PRVKSSSPQRKPGKVFVY-----HFTQSSSANPWPKWTGAMHGYEIEYVF-GIPLS----YSKNY 493

  Fly   494 KTIE-----RMVGMWTSFASSGNPNCPEL-GSAKW 522
            |..|     :::..|.|||.:|.|....| .|..|
 Worm   494 KRREQIFSRKIMQFWASFAKNGTPKLRVLKNSEHW 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	155/552 (28%)
ace-4	NP_496962.1	COesterase	28..562	CDD:395084	155/552 (28%)