Protein Alignment alpha-Est2 and ace-2

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_491141.1
• Gene: ace-2 / 171905
• WormBaseID: WBGene00000036
• Length: 629
• Species: Caenorhabditis elegans
• Alignment Length: 630
• Identity: 159/630 - (25%)
• Similarity: 258/630 - (40%)
• Gaps: 166/630 - (26%)

  Fly    13 MGAQLVGHKVQQYRLSTGHTV-------------ILDTKYGQVRGLQRKTVYDKEPYFAFEGIPY 64
            :|..|..|...|:.|.|...|             ::.|..|.:||:.:  .:|.....||.|:||
 Worm     6 IGRHLTYHVFCQFALVTLFIVRRIEPRSIVRGDHVVHTPLGTIRGVGQ--TFDGAKVSAFLGVPY 68

  Fly    65 AKPPVGDLRFRAPQPPEPWQGVLNCTTNRSKPMQRNMLLGIVEG----------------SEDCL 113
            ||||:|..||:..:..:.|.|.|...|     :.:...|.|...                |||||
 Worm    69 AKPPIGSRRFKMAEMIDRWSGELEART-----LAKTCYLTIDSAFPQFPGAEMWNPPGAISEDCL 128

  Fly   114 HLNVYVKALKSEKPLPVIVWIYGGGFQKGEASRDIYSPDYF-MKKPVVFVAINYRLAALGFLSLK 177
            ::|::|   ..:....|:||||||||..|..|.|:||...| .|:..:.|.:||||...|||...
 Worm   129 NMNIWV---PEDHDGSVMVWIYGGGFFSGTPSLDLYSGSVFAAKEHTIVVNVNYRLGPFGFLYFG 190

  Fly   178 DPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAI 242
            |.. .:.||.||.||.:||||:.:||..|.||.:.:||.||||||||....:....:...|...|
 Worm   191 DDS-PIQGNMGLMDQQLALRWVHENIGAFGGDRSRVTLFGESAGSASTTAHLFAPNSHKYFRNII 254

  Fly   243 MQSGCALSEWVE-SPDN--NWAFRLAQNLGYKGDEKDADVLSFLSKVCARQIAA--IDQDVINLD 302
            .:||..::.|.. :|..  :.:||||:.:.....:.:|.|      .|.|.:.|  :..:..|:.
 Worm   255 AKSGSIINSWASATPPTMLDLSFRLAKKVNCSSPDMNAIV------KCLRSVPAHLVQAEADNIS 313

  Fly   303 -EVRSFLLFAFGPVIEP---YETDHCVVPKRHKDLLSEAWGNDIPVIVGGNSFEG---------- 353
             ::...:.||:.||...   ::.|  |..|    |.::.:..|:.:|.|....||
 Worm   314 GDIGPPMTFAYVPVSSDANFFQGD--VFQK----LANKQFKKDVNIIFGSVKDEGTYWLPYYMSL 372

  Fly   354 -----LFSYQLVRKDPWALKNFHN--ILPREVRETS--------------------SLEG----- 386
                 .|::.:..:||      ||  ::.|:..|.|                    |.|.
 Worm   373 PKYGFAFNHTISAEDP------HNRALITRDHYEESMRAFMPYFAGSKLVLNAFMNSYEHVSTSN 431

  Fly   387 ------QDLLVRRLKQLYFNNEMQESMEMFEALNIFSHRQIWHDTHRFILARQSYAPKTPTYLYR 445
                  :|.:.|.|..|:|...:.:..::... |||.:..:::.|:|      |.|...|.::
 Worm   432 VPEERYRDGVARFLGDLFFTCSLIDFADLISD-NIFGNVYMYYFTYR------SSANPWPKWM-- 487

  Fly   446 FDFDSPHFNQFRRLVCGDRIRGVAHADELSYLF---------YNIIASKLDKSSME-YKTIERMV 500
                                 ||.|..|:.|.|         |       |::.:| .|.:..::
 Worm   488 ---------------------GVMHGYEIEYAFGQPYWRPHLY-------DQTHLEDEKRLSSII 524

  Fly   501 -GMWTSFASSGNPNC--PELGSAKWEAVQLKENAVEKCFNISHDL 542
             .:|.:||::|..:.  |:....:.:|::|.|..::....|..|:
 Worm   525 MQIWANFANTGRTDSFWPQYNKIERKAIELGETTLQGKHRIISDV 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	152/596 (26%)
ace-2	NP_491141.1	COesterase	40..558	CDD:395084	150/583 (26%)