Protein Alignment alpha-Est2 and Ces2c

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_598270.2
• Gene: Ces2c / 171118
• RGDID: 621510
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 608
• Identity: 179/608 - (29%)
• Similarity: 262/608 - (43%)
• Gaps: 120/608 - (19%)

  Fly     7 WPKLIKMGAQLVGHKV------QQYRLSTGHTVILDTKYGQVRGLQRKTVYDKEPYFAFEGIPYA 65
            |...:..|..|:...|      :...:.|.||       |||||........|.....|.|||:|
  Rat     9 WLNAVLFGLLLILIHVWGQDSPESSSIRTTHT-------GQVRGKLDHVRDTKAGVHTFLGIPFA 66

  Fly    66 KPPVGDLRFRAPQPPEPWQGVLNCTTNRSKPMQR------------NMLLGIVEGSEDCLHLNVY 118
            |.|||.|||..|:.||||.||.:.|::.:..:|.            .|:|..:..|||||:||:|
  Rat    67 KAPVGPLRFAPPEDPEPWSGVRDGTSHPAMCLQNIDMLDEVGLTDMKMILSSIPMSEDCLYLNIY 131

  Fly   119 VKALKSE-KPLPVIVWIYGGGFQKGEASR---DIYSPDYFMKKPVVFVAINYRLAALGFLSLKDP 179
            ..|...| ..|||:|.|:||....|.||.   .:.:    :.:.:|.|||.|||..|||.|..|.
  Rat   132 TPAHAHEGSNLPVMVCIHGGALVIGMASMCDGSLLA----VNEDLVVVAIQYRLGVLGFFSTGDE 192

  Fly   180 KLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQ 244
              ...||.|..|||.||||:.||||||.|:||.:|:.|.|||..||...:.:..::||||.|||:
  Rat   193 --HARGNWGYLDQVAALRWVQQNIAHFGGNPNRVTIFGVSAGGTSVSSHVISPMSQGLFHGAIME 255

  Fly   245 SGCA-LSEWVESPDNNWAFRLAQNLGYKGDEKDADVLSFLSKVCARQIAAIDQDVINLDEVRSFL 308
            ||.| |.:.:.......:..:|:..|.:..:.:..|.      |.|..:..:..|||       .
  Rat   256 SGVALLPDLISETSETVSTTVAKLSGCEATDSETLVR------CLRAKSGAEILVIN-------K 307

  Fly   309 LFAFGPVIEPYETDHCVVPKRHKDLLSEAWGNDIPVIVGGNSFEGLFSYQLVRKDPWALKNFHNI 373
            :|...|.:    .|...:|:..|:||:....:.:|.|:|.|:.|...:..:|......:|.
  Rat   308 VFKMIPAV----VDGEFLPRHPKELLASEDFHPVPSIIGVNTDEYCCTIPMVMGTAQIIKE---- 364

  Fly   374 LPRE-----VRETSSL-----EGQDLLVRRLKQLYFNN-------EMQESMEMFEALNIFSHRQI 421
            |.||     :::|::.     |..|||:..    |..|       ::|.:..|.:.|.:....|:
  Rat   365 LSRENLQAVLKDTAAQMMLPPECGDLLMEE----YMGNTDDPQTLQIQYAEMMGDFLFVIPALQV 425

  Fly   422 WHDTHRFILARQSYAPKTPTYLYRFDFDSPHFNQFR-RLVCGDRIRGVAHADELSYLFYNII-AS 484
            .|       .::|:|   |.|.|.|.....:|...| ..|..|      ||||:.::|.:.. ..
  Rat   426 AH-------FQRSHA---PVYFYEFQHAPSYFKNVRPPHVKAD------HADEVPFVFGSFFWGI 474

  Fly   485 KLDKSSMEYKTIERMVGMWTSFASSGNPNCPELGSAKWEAVQLKENAVEKCFNISHD---LEMRD 546
            |:|.:..|.....||:..|.:||..||||..  |...|..             :.||   |::..
  Rat   475 KVDFTEEEKLLSRRMMKYWANFARHGNPNSE--GLPYWPV-------------LDHDEQYLQLDT 524

  Fly   547 LPESD------CLAVWDTFYPRE 563
            .|..|      .|..|....|::
  Rat   525 QPAVDRALKARRLQFWTKTLPQK 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	170/566 (30%)
Ces2c	NP_598270.2	COesterase	32..540	CDD:395084	173/576 (30%)