Protein Alignment alpha-Est2 and LOC1277285

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: XP_316734.5
• Gene: LOC1277285 / 1277285
• VectorBaseID: AGAMI1_010201
• Length: 598
• Species: Anopheles gambiae
• Alignment Length: 605
• Identity: 189/605 - (31%)
• Similarity: 301/605 - (49%)
• Gaps: 87/605 - (14%)

  Fly    10 LIKMGAQLVGHKVQQYRLSTGH---------TVILDTKYGQVRGLQRKTVYDKEP----YFAFEG 61
            ::...|.|:|.|    .:|||.         .:.:..:.|.|.|     |.||.|    |:.|:|
Mosquito     1 MVMRSAPLMGWK----NVSTGSDAEKHMPITRICVQVQQGSVYG-----VRDKLPNGQSYYYFKG 56

  Fly    62 IPYAKPPVGDLRFRAPQPPEPWQ-GVLNCTTNRSKPMQRNMLLGIVEGSEDCLHLNVYVKAL--- 122
            :||||.|||.|||::|.|.|.:. ..|:||..||..:..::|...:.||||.|.||:|...|
Mosquito    57 VPYAKAPVGALRFKSPAPLEKFAVSYLDCTRERSNCLGLDVLTKEISGSEDGLFLNIYTPKLGKR 121

  Fly   123 KSEKPLPVIVWIYGGGFQKGEASRDIYSPDYFMKKPVVFVAINYRLAALGFLSLKDPKLDVPGNA 187
            ...:||||:|:|:|||...|.....:|.|:|.:::.|:.|.:||||..||||.|  |...:.|||
Mosquito   122 DDSEPLPVMVFIHGGGLIGGHGDSSLYLPNYLVQEGVIVVTLNYRLGVLGFLCL--PDAGIEGNA 184

  Fly   188 GLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEW 252
            |||||..||||||:||..|.||.:|:||.|.|:|:.:|:....:.:::..|||||:|||...:|:
Mosquito   185 GLKDQRAALRWISENIGVFGGDASNVTLFGASSGAIAVNFHCLSPESKRYFHKAILQSGSIYTEF 249

  Fly   253 V--ESPDNNWAFRLAQNLGYKGDEKDADVLSFLSKVCARQIAAIDQDVINLDE--VRSFLLFAFG 313
            .  |.|:.. |.|||:.||: ....|.:|...|....||::..:...|:...|  |.......|.
Mosquito   250 AFQEQPEEK-ARRLAKLLGH-SPATDGEVYEILRAAPARKLFELQPLVLTEREKAVERLFQIPFL 312

  Fly   314 PVIEPYETDHCVVPKRHKDLLSEAWGNDIPVIVGGNSFEGLFSYQLVRKDPWALKNFHNILP-RE 377
            ||||..::...::.:...::|||....|||:|:|.|..:|:    :|..|.......:|..| |.
Mosquito   313 PVIERSDSPDALITRHPTEILSEPNSMDIPIILGYNERDGM----MVLIDTIKTLAAYNAEPERF 373

  Fly   378 VRETSSLEGQDLLVRRLKQLYFNNEM----QESMEMFEALNIFSHRQIWHD---------THRFI 429
            :..|.:|:            ||:.|.    :|..|.:     |..|.:..|         |.:::
Mosquito   374 IPRTVALD------------YFSPEARALGEEIREFY-----FGARPVCRDTLNQLTDVFTDKYL 421

  Fly   430 LARQ-------SYAPKTPTYLYRFDFDSPHFNQFRRLVCGDRIRGVAHADELSYLFYN-IIASKL 486
            ||.:       .:..::..:.|||.||. ..|:.:.::....::|.||.||:.|||.: ::.:::
Mosquito   422 LAYRMTVELWARHQRRSKFFGYRFAFDG-LLNKGKAIMSLGTMKGAAHIDEVYYLFSSPLLRTEV 485

  Fly   487 DKSSMEYKTIERMVGMWTSFASSGNPN----CPE-LGSAKWEA---VQLKENAVEKCFNISHD-L 542
            .::...|...:.||.:|::||..|.|.    .|: :...:||.   |...::....|.||::| :
Mosquito   486 PETDRAYGLRKTMVRLWSNFARYGEPTPAQPVPDPVVPFRWEPQPNVPDSQDVPLLCLNITNDGI 550

  Fly   543 EMRDLPESDCLAVWDTFYPR 562
            .|.::||...:..|...:.|
Mosquito   551 AMAEMPEKRRMNFWAGLFER 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	180/564 (32%)
LOC1277285	XP_316734.5	None