Protein Alignment alpha-Est2 and clt

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Alignment Length: 561
• Identity: 209/561 - (37%)
• Similarity: 300/561 - (53%)
• Gaps: 48/561 - (8%)

  Fly    26 RLSTGHTVILDTKYGQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQ-GVLNC 89
            |..:...|.:..|.|.:.|.|:|.|...| |.:|.|:|||:||||:||||:|:|.|.:| ..|:|
  Fly    13 RFCSSMKVKVPVKQGVLVGRQKKLVNGLE-YNSFLGVPYAEPPVGELRFRSPRPLERFQKQELDC 76

  Fly    90 TTNRSKPMQRNMLLGIVEGSEDCLHLNVYVKALKSEK-PLPVIVWIYGGGFQKGEASRDIYSPDY 153
            :...:...||:.....|.||||||.||||...:||.: ||||:|||:||||..|..:.|.:.|..
  Fly    77 SKEGNVSYQRDPFTLEVAGSEDCLFLNVYAPKVKSTRTPLPVMVWIHGGGFFFGNGNSDFHFPAK 141

  Fly   154 FMKKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGE 218
            .|::.|:.|.:||||.|||||||  |:..:.||.|||||.:||.|:.:|||.|||||||:||.||
  Fly   142 LMEQEVIVVTLNYRLGALGFLSL--PEEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGE 204

  Fly   219 SAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEWV---ESPDNNWAFRLAQNLG---YKGDEKDA 277
            |||.:|||:.......:.||||||||||.|..|||   |:|..  ..|||:.||   :.||.|
  Fly   205 SAGGSSVHLHTFARHAKRLFHKAIMQSGTANMEWVFQNEAPAK--TRRLAELLGGGDFGGDSK-- 265

  Fly   278 DVLSFL--SKVCARQIAAIDQDVINLDEVRSFLLFAFGPVIEPYET-----DHCVVPKRH-KDLL 334
            .:|:||  .|.....|.|....|::.||.|..|.|||.||:|...:     :..::...| ||.|
  Fly   266 ALLTFLQSEKATPTAILANTLKVLSPDERRRHLPFAFKPVVEDSSSPDRFLEQDIMELMHKKDCL 330

  Fly   335 SEAWGNDIPVIVGGNSFEGLFSYQLVRKDPWALKNFHN----ILPRE-VRETSSLEGQDLLVRRL 394
                 ..:|||:|.||.|||   .:|.|....|:.:.:    ::||. |.:..:.|.|: ....:
  Fly   331 -----GSMPVIMGYNSAEGL---AIVVKAKQKLEAYEDDLARLVPRNLVLDPQAPEAQE-AASDI 386

  Fly   395 KQLYFNNEMQESMEMFEALNIFSHRQIWHDTHRFILARQSYAPKTPTYLYRFDFDSPHFNQFRRL 459
            :..:||.:......|...:::||......|..|.:....|...::|.|.||.|:.... |.::::
  Fly   387 RAFFFNGQALSKENMDNLVDLFSDYHFSMDLQRAVEIHASCQTQSPLYFYRLDYVGGR-NLYKKI 450

  Fly   460 VCGDRIRGVAHADELSYLFYNIIASKLDKSSMEYKTIERMVGMWTSFASSGNPNCPELGSAKWEA 524
            ...:.:|||||||::.||| .:...:.:.:..:....||:..||.:||..|.|      |..|:.
  Fly   451 FQNEDLRGVAHADDICYLF-QMAGDETEMNRDDLMVTERLCEMWANFARDGKP------SPIWKP 508

  Fly   525 VQLKENAVE---KCFNISHDLEMRDLPESDCLAVWDTFYPR 562
            |:...|...   .|..|..:|:|...|:.:.:..|.:.|.|
  Fly   509 VKKPHNGEPIQLDCLLIDRELKMCSNPDGERMDFWRSMYRR 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	204/545 (37%)
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	204/544 (38%)